Infected episiotomy/laceration (organ or space infection) № of participants: 3420 (1 RCT) · Women undergoing operative vaginal delivery
Any antibiotics showed no clear difference in infected episiotomy/laceration (organ or space infection) № of… compared with placebo or no treatment (low certainty).
1 finding from 1 review
RR 0.11 [0.01, 2.05]
Studies not reported
Low
Infected episiotomy/laceration (wound breakdown) № of participants: 2593 (1 RCT) · Women undergoing operative vaginal delivery
Any antibiotics probably leads to lower infected episiotomy/laceration (wound breakdown) № of participants:… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 0.52 [0.43, 0.63]
Studies not reported
Moderate
Endometritis · Women undergoing operative vaginal delivery
Any antibiotics showed no clear difference in endometritis № of participants: 3813 (2 RCTs) compared with placebo or no treatment (low certainty).
1 finding from 1 review
RR 0.32 [0.04, 2.64]
Studies not reported
Low
Urinary tract infection ‐ not measured · Women undergoing operative vaginal delivery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious infectious complications · Women undergoing operative vaginal delivery
Any antibiotics leads to lower serious infectious complications № of participants: 3420 (1 RCT) compared with placebo or no treatment (high certainty).
1 finding from 1 review
RR 0.44 [0.22, 0.89]
Studies not reported
High
Maternal adverse reactions · Women undergoing operative vaginal delivery
Any antibiotics showed no clear difference in maternal adverse reactions № of participants: 2593 (1 RCT) compared with placebo or no treatment (low certainty).
1 finding from 1 review
RR 2 [0.18, 22.05]
Studies not reported
Low
Subjective improvement in symptoms at 1 month and 3 months · adult participants with chronic blepharitis
1 finding from 1 review
Measurements of eradication or decrease in numbers of colonies of positive cultures of bacteria · adult participants with chronic blepharitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical signs—Schirmer test scores at 1 month (mm/5 min) · adult participants with chronic blepharitis
1 finding from 1 review
Clinical signs—TBUT at 1 month (seconds) · adult participants with chronic blepharitis
1 finding from 1 review
Adverse events at 1 month · adult participants with chronic blepharitis
It is very uncertain whether oral antibiotics changes adverse events at 1 month compared with placebo (very low certainty).
1 finding from 1 review
Quality of life measures · adult participants with chronic blepharitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Economic costs and benefits of different interventions · adult participants with chronic blepharitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Deaths · any indication
Other adverse events in people taking macrolide antibiotics showed no clear difference in deaths compared with placebo (low certainty).
1 finding from 1 review
Cardiac disorders · any indication
It is very uncertain whether other adverse events in people taking macrolide antibiotics changes cardiac disorders compared with placebo (very low certainty).
1 finding from 1 review
Hearing loss · any indication
Other adverse events in people taking macrolide antibiotics showed no clear difference in hearing loss compared with placebo (low certainty).
1 finding from 1 review
Taste disturbance · any indication
Other adverse events in people taking macrolide antibiotics may leads to higher taste disturbance compared with placebo (low certainty).
1 finding from 1 review
Hepatobiliary disorders · any indication
It is very uncertain whether other adverse events in people taking macrolide antibiotics changes hepatobiliary disorders compared with placebo (very low certainty).
1 finding from 1 review
Gastrointestinal disorders not otherwise specified · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher gastrointestinal disorders not otherwise specified compared with placebo (moderate certainty).
1 finding from 1 review
Abdominal pain · any indication
Gastrointestinal adverse events in people taking macrolide antibiotics may leads to higher abdominal pain compared with placebo (low certainty).
1 finding from 1 review