Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

594 questions · 624 findings · 70 reviews

No studies found 151 · 24.2%GRADE not reported 53 · 8.5%Very low 174 · 27.9%Low 129 · 20.7%Moderate 82 · 13.1%High 35 · 5.6%

Antibiotics vs control

Sore throat · patients with sore throat

Antibiotics probably leads to lower sore throat: day 3 compared with control (moderate certainty).

2 findings from 1 review

Antibiotics vs placebo or no intervention

Cardiovascular mortality · patients with coronary heart disease

Antibiotics leads to higher cardiovascular mortality at 24±6 months compared with placebo or no intervention (high certainty).

2 findings from 1 review

Antibiotics vs placebo or no intervention

Myocardial infarction · patients with coronary heart disease

Antibiotics showed no clear difference in myocardial infarction at 24±6 months compared with placebo or no intervention (moderate certainty).

2 findings from 1 review