What do systematic reviews say?

Antibiotics vs no antibiotics

Antibiotics showed no clear difference in mortality (before discharge) compared with control (no antibiotics) (low certainty).

• Antibiotics for neonates born through meconium‐stained amniotic fluid 2017 · Cochrane Headline outcomes only
  RR 1.69 [0.23, 12.53]
  3 studies · 445 participants
  Low

Antibiotics vs no antibiotics

Antibiotics showed no clear difference in mortality (before discharge) compared with control (no antibiotics) (low certainty).

• Antibiotics for neonates born through meconium‐stained amniotic fluid 2017 · Cochrane Headline outcomes only
  RR 1.07 [0.22, 5.18]
  1 study · 250 participants
  Low

Antibiotics on removal of central venous catheter vs no antibiotics

• Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 88 participants
  Low

Antibiotics on removal of central venous catheter vs no antibiotics

• Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 88 participants
  Low