Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

17 questions · 17 findings · 3 reviews · Pregnancy and Childbirth

No studies found 0 · 0%GRADE not reported 7 · 41.2%Very low 7 · 41.2%Low 2 · 11.8%Moderate 1 · 5.9%High 0 · 0%

Antibiotic prophylaxis vs no treatment or placebo

Adverse effects of antibiotics (skin rash) · Women who had normal vaginal births

It is very uncertain whether routine antibiotic prophylaxis changes adverse effects of antibiotics (skin rash) compared with no treatment or placebo (very low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment

Incidence of episiotomy wound dehiscence without wound infection · women with episiotomy repair following vaginal birth

It is very uncertain whether antibiotic prophylaxis changes incidence of episiotomy wound dehiscence without wound infection compared with no treatment (very low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment

Infection rate at 2 weeks postpartum ‐ perineal wound infection in third‐ or fourth‐degree tear · Women with third‐ and fourth‐degree perineal tear during vaginal birth

Antibiotic prophylaxis probably leads to lower infection rate at 2 weeks postpartum ‐ perineal wound infection in… compared with no treatment (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment

Infection rate at 6 weeks postpartum ‐ perineal wound infection in third‐ or fourth‐degree tear · Women with third‐ and fourth‐degree perineal tear during vaginal birth

Antibiotic prophylaxis showed no clear difference in infection rate at 6 weeks postpartum ‐ perineal wound infection in… compared with no treatment (low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment or placebo

Wound infection (episiotomy dehiscence) · Women who had normal vaginal births

It is very uncertain whether routine antibiotic prophylaxis changes wound infection (episiotomy dehiscence) compared with no treatment or placebo (very low certainty).

1 finding from 1 review