Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

57 questions · 61 findings · 10 reviews

No studies found 7 · 11.5%GRADE not reported 7 · 11.5%Very low 21 · 34.4%Low 13 · 21.3%Moderate 13 · 21.3%High 0 · 0%

Antibiotic prophylaxis vs no treatment

Incidence of episiotomy wound dehiscence without wound infection · women with episiotomy repair following vaginal birth

It is very uncertain whether antibiotic prophylaxis changes incidence of episiotomy wound dehiscence without wound infection compared with no treatment (very low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment

Infection rate at 2 weeks postpartum ‐ perineal wound infection in third‐ or fourth‐degree tear · Women with third‐ and fourth‐degree perineal tear during vaginal birth

Antibiotic prophylaxis probably leads to lower infection rate at 2 weeks postpartum ‐ perineal wound infection in… compared with no treatment (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs no treatment

Infection rate at 6 weeks postpartum ‐ perineal wound infection in third‐ or fourth‐degree tear · Women with third‐ and fourth‐degree perineal tear during vaginal birth

Antibiotic prophylaxis showed no clear difference in infection rate at 6 weeks postpartum ‐ perineal wound infection in… compared with no treatment (low certainty).

1 finding from 1 review

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

Mortality or serious adverse events requiring hospital admission · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

Development of endocarditis due to other (non-dental) causes · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis vs no treatment or placebo

Wound infection (episiotomy dehiscence) · Women who had normal vaginal births

It is very uncertain whether routine antibiotic prophylaxis changes wound infection (episiotomy dehiscence) compared with no treatment or placebo (very low certainty).

1 finding from 1 review