Findings

What do systematic reviews say?

37 questions · 38 findings · 6 reviews · Eyes and Vision

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No studies found 13 · 34.2%GRADE not reported 0 · 0%Very low 9 · 23.7%Low 11 · 28.9%Moderate 5 · 13.2%High 0 · 0%

Antibiotics vs control

Antibiotic resistance · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs control

Active trachoma · people (any age) with active trachoma

Antibiotic may leads to lower active trachoma Clinical assessment: active trachoma defined as TF,… compared with control (low certainty).

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
RR 0.78 [0.69, 0.89]
9 studies · 1961 participants
Low

Antibiotics vs control

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

Antibiotic showed no clear difference in ocular C trachomatis infection Positive test for C trachomatis… compared with control (low certainty).

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
RR 0.81 [0.63, 1.04]
4 studies · 297 participants
Low

Antibiotics vs control

Adverse effects · people (any age) with active trachoma

Antibiotic may leads to lower adverse effects compared with control (low certainty).

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1961 participants
Low

Antibiotics vs no treatment

Change in BCVA (lower logMAR indicate better vision) · People with toxoplasma retinochoroiditis

1 finding from 1 review

Antibiotics versus no treatment for toxoplasma retinochoroiditis 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 93 participants
Low

Antibiotics vs no treatment

or more recurrences of retinochoroiditis · People with toxoplasma retinochoroiditis

Antibiotic probably leads to lower or more recurrences of retinochoroiditis compared with no treatment (moderate certainty).

1 finding from 1 review

Antibiotics versus no treatment for toxoplasma retinochoroiditis 2016 · Cochrane Headline outcomes only
RR 0.26 [0.11, 0.63]
3 studies · 227 participants
Moderate

Antibiotics vs no treatment

Improvement in intraocular inflammation · People with toxoplasma retinochoroiditis

Antibiotic showed no clear difference in improvement in intraocular inflammation compared with no treatment (low certainty).

1 finding from 1 review

Antibiotics versus no treatment for toxoplasma retinochoroiditis 2016 · Cochrane Headline outcomes only
RR 1.76 [0.98, 3.19]
1 study · 29 participants
Low

Antibiotics vs no treatment

Size of lesion · People with toxoplasma retinochoroiditis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus no treatment for toxoplasma retinochoroiditis 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment

Adverse events · People with toxoplasma retinochoroiditis

Antibiotic showed no clear difference in adverse events compared with no treatment (low certainty).

1 finding from 1 review

Antibiotics versus no treatment for toxoplasma retinochoroiditis 2016 · Cochrane Headline outcomes only
RR 3 [0.37, 24.17]
1 study · 20 participants
Low

Antibiotics vs placebo

Clinical efficacy (RR > 1 is favored) · Participants with acute bacterial conjunctivitis

1 finding from 1 review

Antibiotics versus placebo for acute bacterial conjunctivitis 2023 · Cochrane Headline outcomes only
no estimate extracted
4 participants
Moderate

Antibiotics vs placebo

Microbiological efficacy (RR > 1 favored) · Participants with acute bacterial conjunctivitis

1 finding from 1 review

Antibiotics versus placebo for acute bacterial conjunctivitis 2023 · Cochrane Headline outcomes only
no estimate extracted
8 participants
Moderate

Antibiotics vs placebo

Treatment incompletion (RR < 1 favored) · Participants with acute bacterial conjunctivitis

Antibiotics probably leads to lower treatment incompletion (RR < 1 favored) compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics versus placebo for acute bacterial conjunctivitis 2023 · Cochrane Headline outcomes only
RR 0.64 [0.52, 0.78]
13 studies · 5573 participants
Moderate

Antibiotics vs placebo

Persistent clinical infection after one course of treatment (RR < 1 favored) · Participants with acute bacterial conjunctivitis

Antibiotics probably leads to lower persistent clinical infection after one course of treatment (RR < 1… compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics versus placebo for acute bacterial conjunctivitis 2023 · Cochrane Headline outcomes only
RR 0.73 [0.65, 0.81]
19 studies · 5280 participants
Moderate

Antibiotics vs placebo

Cost‐effectiveness of treatment · Participants with acute bacterial conjunctivitis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus placebo for acute bacterial conjunctivitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo

Treatment‐associated ocular complications (RR < 1 or RD ≤ 0 favored) · Participants with acute bacterial conjunctivitis

It is very uncertain whether antibiotics changes treatment‐associated ocular complications (RR < 1 or RD ≤ 0 favored) compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics versus placebo for acute bacterial conjunctivitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Antibiotics vs placebo

Treatment‐associated systemic complications (RR < 1 favored) · Participants with acute bacterial conjunctivitis

1 finding from 1 review

Antibiotics versus placebo for acute bacterial conjunctivitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical antibiotics vs another topical antibiotic or placebo

Risk of any ocular infection within 1 month following corneal abrasion · children and adults with corneal abrasion

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical antibiotics vs another topical antibiotic or placebo

Time to clinical cure · children and adults with corneal abrasion

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical antibiotics vs another topical antibiotic or placebo

Change in pain intensity from baseline to 1 month · children and adults with corneal abrasion

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs another topical antibiotic or placebo

Recurrent corneal erosion within 1 year · children and adults with corneal abrasion

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found