Antibiotics probably leads to lower rheumatic fever (within 2 months, clinical diagnosis) compared with control (moderate certainty).
Antibiotics showed no clear difference in glomerulonephritis (within 1 month, clinical diagnosis) compared with control (low certainty).
Antibiotics leads to lower quinsy (within 2 months, clinical diagnosis) compared with control (high certainty).
Antibiotics leads to lower otitis media (within 14 days, clinical diagnosis) compared with control (high certainty).
Antibiotics showed no clear difference in all‐cause mortality at maximum compared with placebo or no intervention (high certainty).
The review found no eligible studies for this question.
Antibiotics leads to higher cardiovascular mortality at 24±6 months compared with placebo or no intervention (high certainty).
Antibiotics showed no clear difference in myocardial infarction at 24±6 months compared with placebo or no intervention (moderate certainty).
Antibiotics showed no clear difference in stroke at 24±6 months compared with placebo or no intervention (high certainty).
Antibiotics probably leads to higher sudden cardiac death at 24±6 months compared with placebo or no intervention (moderate certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Antibiotics leads to higher all‐cause mortality at 24±6 months compared with placebo or no intervention (high certainty).
The review found no eligible studies for this question.
Antibiotics may leads to lower development of pyelonephritis compared with no treatment (low certainty).
Antibiotics may leads to lower preterm birth < 37 weeks compared with no treatment (low certainty).
Antibiotics may leads to lower birthweight < 2500 g compared with no treatment (low certainty).
The review found no eligible studies for this question.
Antibiotics showed no clear difference in all adverse events compared with placebo or usual care (low certainty).