Treatment failure · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in treatment failure compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in adverse events compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Prophylactic antibiotic at one dose or duration vs Same antibiotic at a different dose or duration
Outcome not reported · Adults undergoing dental implant placement
1 finding from 1 review
No conclusive information can be derived from the only trial that compared three different durations of antibiotic prophylaxis, since no event (implant or prosthesis failures, infections or adverse events) occurred in…
1 study · 100 participants
GRADE not reported
Prosthesis failure · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in prosthesis failure compared with no antibiotics or placebo; GRADE not reported.
1 finding from 1 review
Postoperative infection · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in postoperative infection compared with no antibiotics or placebo; GRADE not reported.
1 finding from 1 review
Implant failure · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).
1 finding from 1 review
Adverse events · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.
1 finding from 1 review
Wound infection · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) compared with placebo (very low certainty).
2 findings from 1 review
DSSI · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in DSSI compared with placebo (moderate certainty).
1 finding from 1 review
DSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in DSSI ‐ low infection risk environment compared with placebo (moderate certainty).
1 finding from 1 review
DSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in DSSI ‐ high infection risk environment compared with placebo (low certainty).
1 finding from 1 review
All wound infections (SSSI + DSSI) ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ low infection risk environment compared with placebo (very low certainty).
2 findings from 1 review
All wound infections (SSSI + DSSI) ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ high infection risk environment compared with placebo (very low certainty).
2 findings from 1 review
SSSI · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis probably leads to lower SSSI compared with placebo (moderate certainty).
1 finding from 1 review
SSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in SSSI ‐ low infection risk environment compared with placebo (moderate certainty).
1 finding from 1 review
SSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes SSSI ‐ high infection risk environment compared with placebo (very low certainty).
1 finding from 1 review
Incidence of episiotomy wound infection with wound dehiscence · women with episiotomy repair following vaginal birth
It is very uncertain whether antibiotic prophylaxis changes incidence of episiotomy wound infection with wound dehiscence compared with no treatment (very low certainty).
1 finding from 1 review
RR 0.13 [0.01, 2.28]
73 participants
Very low
Incidence of episiotomy wound dehiscence without wound infection · women with episiotomy repair following vaginal birth
It is very uncertain whether antibiotic prophylaxis changes incidence of episiotomy wound dehiscence without wound infection compared with no treatment (very low certainty).
1 finding from 1 review
RR 0.82 [0.29, 2.34]
73 participants
Very low
Incidence of puerperal infection (endometritis) · women with episiotomy repair following vaginal birth
1 finding from 1 review
no estimate extracted
73 participants
Very low
Incidence of severe maternal infectious morbidity · women with episiotomy repair following vaginal birth
1 finding from 1 review