Antibiotic resistance · people with bronchiectasis
28 days on/off antibiotic regimen leads to higher antibiotic resistance compared with 28 days on/off placebo regimen (high certainty).
1 finding from 1 review
OR 2.2 [1.42, 3.42]
Studies not reported
High
Antibiotic resistance · people with bronchiectasis
14 days on/off antibiotic regimen leads to higher antibiotic resistance compared with 14 days on/off placebo regimen (high certainty).
1 finding from 1 review
OR 2.14 [1.36, 3.35]
Studies not reported
High
Neonatal mortality ‐ oral antibiotic · neonates with sepsis
Comparison 1: route of antibiotic may leads to lower neonatal mortality ‐ oral antibiotic compared with standard care (low certainty).
1 finding from 1 review
Neonatal mortality ‐ injectable antibiotic · neonates with sepsis
Comparison 1: route of antibiotic probably leads to lower neonatal mortality ‐ injectable antibiotic compared with standard care (moderate certainty).
1 finding from 1 review
Neonatal mortality ‐ oral + injectable antibiotics · neonates with sepsis
Comparison 1: route of antibiotic showed no clear difference in neonatal mortality ‐ oral + injectable antibiotics compared with standard care (moderate certainty).
1 finding from 1 review
Number of participants with symptomatic UTI · primary VUR
Antibiotic prophylaxis showed no clear difference in symptomatic UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).
2 findings from 1 review
Febrile UTI by 1 to 2 years: antibiotics versus no prophylaxis · primary VUR
Antibiotic prophylaxis showed no clear difference in febrile UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).
1 finding from 1 review
New renal parenchymal defects (scars and thinning) on IVP: unit of analysis (children) at 4 to 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR
Surgical reimplantation of ureters plus antibiotics showed no clear difference in new renal parenchymal defects (scars and thinning) on IVP: unit of… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
Correction of VUR: unit of analysis (children) after 3 years: surgical correction + antibiotics versus antibiotics alone · primary VUR
It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes correction of VUR: unit of analysis (children) after 3 years:… compared with antibiotics alone (very low certainty).
1 finding from 1 review
Number of participants with symptomatic UTI · primary VUR
Surgical reimplantation of ureters plus antibiotics showed no clear difference in all symptomatic UTI by 4 to 5 years: surgical correction +… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
Febrile UTI by 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR
Surgical reimplantation of ureters plus antibiotics probably leads to lower febrile UTI by 5 years: surgical correction + antibiotics versus… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
Repeat positive urine culture · primary VUR
Surgical reimplantation of ureters plus antibiotics showed no clear difference in repeat positive urine cultures by 4 to 5 years: surgical correction… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
Risk of any ocular infection within 1 month following corneal abrasion · children and adults with corneal abrasion
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Time to clinical cure · children and adults with corneal abrasion
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Change in pain intensity from baseline to 1 month · children and adults with corneal abrasion
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent corneal erosion within 1 year · children and adults with corneal abrasion
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Visual acuity · children and adults with corneal abrasion
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life at 1 month · children and adults with corneal abrasion
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · children and adults with corneal abrasion
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Surgical site infection · people presenting for surgery where healing of surgical wound planned to be by primary intention
Topical antibiotics probably leads to lower surgical site infection compared with no topical antibiotic. (moderate certainty).
1 finding from 1 review