Findings

What do systematic reviews say?

43 questions · 43 findings · 7 reviews

No studies found 19 · 44.2%GRADE not reported 6 · 14%Very low 1 · 2.3%Low 8 · 18.6%Moderate 9 · 20.9%High 0 · 0%

Time to heal mucositis (days) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Allopurinol mouthwash led to lower time to heal mucositis (days) compared with placebo; GRADE not reported.

1 finding from 1 review

Interventions for treating oral mucositis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
MD -4.50 [-5.77, -3.23]
1 study · 44 participants
GRADE not reported

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Allopurinol mouthrinse led to lower oral mucositis (moderate to severe) compared with placebo/no treatment; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes
Median 28 days
RR 0.66 [0.5, 0.86]
2 studies
GRADE not reported

Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Allopurinol mouthrinse showed no clear difference in oral mucositis (any severity) compared with placebo/no treatment; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes
Median 28 days
RR 0.77 [0.5, 1.19]
4 studies
GRADE not reported