Question · asked by 1 review

Allopurinol mouthwash vs placebo: Time to heal mucositis (days)

Population
People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Intervention
Allopurinol mouthwash
Comparison
placebo
Outcome
Time to heal mucositis (days)

Allopurinol mouthwash led to lower time to heal mucositis (days) compared with placebo; GRADE not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Allopurinol mouthwash vs Placebo
Time to heal mucositis (days) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Allopurinol mouthwash led to lower time to heal mucositis (days) compared with placebo; GRADE not reported.
Interventions for treating oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomes
MD -4.50 [-5.77, -3.23]1 study · 44 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral mucositis for patients with cancer receiving treatment
2010 · Cochrane All outcomes
2010-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.