Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · HIV/AIDS

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 50%High 2 · 50%

Death at 1 month (adults) · patients with Pneumocystis jiroveci pneumonia and HIV infection

Adjunctive corticosteroids leads to lower death at 1 month (adults) compared with no such treatment (high certainty).

1 finding from 1 review

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection 2015 · Cochrane Headline outcomes only
RR 0.56 [0.32, 0.98]
6 studies · 489 participants
High

Death at 3 to 4 months (adults) · patients with Pneumocystis jiroveci pneumonia and HIV infection

Adjunctive corticosteroids leads to lower death at 3 to 4 months (adults) compared with no such treatment (high certainty).

1 finding from 1 review

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection 2015 · Cochrane Headline outcomes only
RR 0.59 [0.41, 0.85]
5 studies · 448 participants
High

Death in hospital; children · patients with Pneumocystis jiroveci pneumonia and HIV infection

Adjunctive corticosteroids showed no clear difference in death in hospital; children compared with no such treatment (moderate certainty).

1 finding from 1 review

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection 2015 · Cochrane Headline outcomes only
RR 0.81 [0.51, 1.29]
1 study · 100 participants
Moderate

Need for mechanical ventilation · patients with Pneumocystis jiroveci pneumonia and HIV infection

Adjunctive corticosteroids probably leads to lower need for mechanical ventilation at 1 month compared with no such treatment (moderate certainty).

1 finding from 1 review

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection 2015 · Cochrane Headline outcomes only
RR 0.38 [0.2, 0.73]
3 studies · 388 participants
Moderate