Findings

What do systematic reviews say?

2 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Dental caries · Children (<18 years) with vs without dental caries

After removing Zhang 2006, the over-dominant model at BsmI(rs1544410) remained non-significant (OR 0.85); ungraded.

2 findings from 1 review

Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomes
Over-dominant model (AA+GG vs GA), Zhang 2006 removed · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Sensitivity analysis (Zhang 2006 excluded)
OR 0.85 [0.48, 1.49]
3 studies · 1329 participants
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomes
Over-dominant model (AA+GG vs GA) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India)
OR 0.60 [0.28, 1.25]
4 studies · 1741 participants
GRADE not reported

Dental caries · Children (<18 years) with vs without dental caries

FokI(rs2228570) over-dominant model: AA+GG vs AG was not significantly associated with dental caries (OR 1.04); ungraded.

1 finding from 1 review

Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomes
Over-dominant model (AA+GG vs AG) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India)
OR 1.04 [0.64, 1.70]
3 studies · 855 participants
GRADE not reported