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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
555 questions in 79 reviews · Musculoskeletal
current versionsNo studies 555 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Methotrexate vs placebo Outcomes(time frame of absolute effects) · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Treatment responsea · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Function · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Pain · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Participant global assessment of well‐being · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs alternative disease‐modifying antirheumatic drugs Outcomes(time frame of absolute effects) · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs alternative disease‐modifying antirheumatic drugs Sustained clinically inactive diseasec · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs alternative disease‐modifying antirheumatic drugs Pain · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs placebo Sustained clinically inactive diseasec · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs placebo Function · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Outcomes(time frame of absolute effects) · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane | no estimate extracted | NR | No studies |
Intermittent/cyclic etidronate 400 mg/day vs placebo Wrist fractures № of participants: 0 (0 RCTs) · postmenopausal women with a lower risk for fracturesa Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2024) · Cochrane | no estimate extracted | NR | No studies |
Intermittent/cyclic etidronate 400 mg/day vs placebo Clinical vertebral fractures № of participants: 0 (0 RCTs) · postmenopausal women with a higher risk for fracturesa Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2024) · Cochrane | no estimate extracted | NR | No studies |
Manual therapy, prescribed exercises or both vs minimal or no intervention Proportion with a serious adverse event · lateral elbow pain Manual therapy and exercise for lateral elbow pain (2024) · Cochrane | no estimate extracted | NR | No studies |
Manual therapy, prescribed exercises or both vs placebo Quality of life · lateral elbow pain Manual therapy and exercise for lateral elbow pain (2024) · Cochrane | no estimate extracted | NR | No studies |
Manual therapy, prescribed exercises or both vs placebo Participant‐reported treatment success · lateral elbow pain Manual therapy and exercise for lateral elbow pain (2024) · Cochrane | no estimate extracted | NR | No studies |
Manual therapy, prescribed exercises or both vs placebo Proportion of withdrawals · lateral elbow pain Manual therapy and exercise for lateral elbow pain (2024) · Cochrane | no estimate extracted | NR | No studies |
Manual therapy, prescribed exercises or both vs placebo Proportion with adverse events · lateral elbow pain Manual therapy and exercise for lateral elbow pain (2024) · Cochrane | no estimate extracted | NR | No studies |
Manual therapy, prescribed exercises or both vs placebo Proportion with a serious adverse event · lateral elbow pain Manual therapy and exercise for lateral elbow pain (2024) · Cochrane | no estimate extracted | NR | No studies |
McKenzie therapy vs manual therapy Adverse events · patients with non‐specific acute and subacute low back pain The McKenzie method for (sub)acute non‐specific low back pain (2023) · Cochrane | no estimate extracted | NR | No studies |
McKenzie therapy vs other interventions Pain intensity: short‐term (closest to 2 weeks) · patients with non‐specific acute and subacute low back pain The McKenzie method for (sub)acute non‐specific low back pain (2023) · Cochrane | no estimate extracted | NR | No studies |
McKenzie therapy vs other interventions Pain intensity: intermediate‐term (closest to 3 months) · patients with non‐specific acute and subacute low back pain The McKenzie method for (sub)acute non‐specific low back pain (2023) · Cochrane | no estimate extracted | NR | No studies |
McKenzie therapy vs other interventions Adverse events · patients with non‐specific acute and subacute low back pain The McKenzie method for (sub)acute non‐specific low back pain (2023) · Cochrane | no estimate extracted | NR | No studies |
McKenzie therapy vs minimal intervention Adverse events · patients with non‐specific acute and subacute low back pain The McKenzie method for (sub)acute non‐specific low back pain (2023) · Cochrane | no estimate extracted | NR | No studies |
Vitamin D vs placebo Quality of life · premenopausal women (age 18–32.7 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Vitamin D vs placebo Vertebral fracture · premenopausal women (age 18–32.7 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Vitamin D vs placebo Non‐vertebral fracture · premenopausal women (age 18–32.7 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Vitamin D vs placebo Serious adverse events · premenopausal women (age 18–32.7 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium and vitamin D vs placebo Quality of life · premenopausal women (ages 18–36 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium and vitamin D vs placebo Vertebral fracture · premenopausal women (ages 18–36 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium and vitamin D vs placebo Non‐vertebral fracture · premenopausal women (ages 18–36 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium and vitamin D vs placebo Serious adverse events · premenopausal women (ages 18–36 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium vs placebo Quality of life · premenopausal women (age 18−47.3 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium vs placebo Vertebral fracture · premenopausal women (age 18−47.3 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium vs placebo Non‐vertebral fracture · premenopausal women (age 18−47.3 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Calcium vs placebo Serious adverse events · premenopausal women (age 18−47.3 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Vitamin D vs placebo Total hip BMD · premenopausal women (age 18–32.7 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Vitamin D vs placebo Lumbar spine BMD · premenopausal women (age 18–32.7 years) Calcium and vitamin D for increasing bone mineral density in premenopausal women (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Quality of life ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Serious adverse events ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Serious adverse events ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Quality of life ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Disease activity ‐ not measured · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Quality of life ‐ not measured · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Serious adverse events ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Prefabricated foot orthoses vs shoes Quality of life · children with asymptomatic flat feet Foot orthoses for treating paediatric flat feet (2022) · Cochrane | no estimate extracted | NR | No studies |
Prefabricated foot orthoses vs shoes Treatment success · children with asymptomatic flat feet Foot orthoses for treating paediatric flat feet (2022) · Cochrane | no estimate extracted | NR | No studies |
Prefabricated foot orthoses vs shoes Adverse events · children with asymptomatic flat feet Foot orthoses for treating paediatric flat feet (2022) · Cochrane | no estimate extracted | NR | No studies |
Prefabricated foot orthoses vs shoes Serious adverse events · children with asymptomatic flat feet Foot orthoses for treating paediatric flat feet (2022) · Cochrane | no estimate extracted | NR | No studies |
Custom foot orthoses vs prefabricated foot orthoses Function or disability · children with asymptomatic flat feet Foot orthoses for treating paediatric flat feet (2022) · Cochrane | no estimate extracted | NR | No studies |