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Evidence found and GRADE certainty

313 questions · 321 findings · 77 reviews · Dental caries · All outcomes

No studies found 321 · 100%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Partial pulpotomy vs Full (complete) pulpotomy

Patient- and clinical-reported outcomes (tooth survival, clinical/radiographic success, pain) · Asymptomatic permanent teeth with deep caries (no symptoms)

No studies compared partial versus full pulpotomy in asymptomatic permanent teeth with deep caries, so no evidence is available.

1 finding from 1 review

Dental cavity liner (e.g. calcium hydroxide, glass ionomer, resin-modified glass ionomer, or flowable composite) placed under the restoration vs No cavity liner or a different liner material

Oral health-related quality of life · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis

No included study reported oral health-related quality of life (a planned outcome), so no evidence is available.

1 finding from 1 review

Pulp and periapical diseases vs Without pulp and periapical diseases

Lacunar stroke · adults

No eligible studies were found for the association between pulp and periapical diseases and lacunar stroke in the meta-analysis.

1 finding from 1 review

Microinvasive techniques (resin infiltration, resin/GIC sealant, or glass ionomer varnish) vs Conventional restoration

Radiographic proximal caries lesion progression · Children and adults with non-cavitated proximal (interproximal) caries lesions in primary and/or permanent teeth (ages 3-45)

No eligible studies compared microinvasive techniques with invasive (restorative) treatment; this planned comparison had zero included studies.

1 finding from 1 review

Partial pulpotomy vs Full (complete) pulpotomy

Oral health-related quality of life · Mature permanent (molar) teeth with deep caries and symptoms indicative of irreversible pulpitis (spontaneous pain)

No included study reported oral health-related quality of life (a planned outcome), so no evidence is available.

1 finding from 1 review

Partial pulpotomy vs Full (complete) pulpotomy

Patient- and clinical-reported outcomes (tooth survival, clinical/radiographic success, pain) · Permanent teeth with deep caries and reversible pulpitis (non-spontaneous pain)

No studies compared partial versus full pulpotomy in permanent teeth with reversible pulpitis (non-spontaneous pain), so no evidence is available.

1 finding from 1 review

High-intensity sweeteners other than stevia (aspartame, sucralose, saccharin) in food products vs Any comparator (dietary sugar, no treatment, or other sweetener)

Effects of non-stevia high-intensity sweeteners (aspartame, sucralose, saccharin) on cariogenic bacteria in dental plaque or saliva · healthy people

No eligible studies evaluated high-intensity sweeteners such as aspartame, sucralose, or saccharin for their effect on cariogenic bacteria.

1 finding from 1 review

Dietary advice on how to achieve a healthy diet for infants (tailored advice focused on a diet low in saturated fat and cholesterol intake) vs usual care

Dental caries · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

The review found no eligible studies for this question.

2 findings from 1 review

Oral health education/promotion (oral hygiene advice plus diet and feeding practice advice) combined with clinical treatment for mother's dentition (basic restorative and preventive; 1 trial included CHX varnish application) vs usual care

Dental caries · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Dental caries · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

The review found no eligible studies for this question.

2 findings from 1 review