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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

542 questions in 42 reviews · Skin

current versions
No studies 542 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
hAMMSC‐CM + vitamin C vs hAMMSC‐CM
Secondary outcome: acceptability of treatment · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin C vs hAMMSC‐CM
Secondary outome: cost of intervention · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin E vs hAMMSC‐CM
Primary outcome: prevention of ulcer · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin E vs hAMMSC‐CM
Secondary outcome: quality of life · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin E vs hAMMSC‐CM
Secondary outcome: acceptability of treatment · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin E vs hAMMSC‐CM
Secondary outome: cost of intervention · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin E vs hAMMSC‐CM + vitamin C
Primary outcome: prevention of ulcer · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin E vs hAMMSC‐CM + vitamin C
Secondary outcome: quality of life · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
hAMMSC‐CM + vitamin E vs hAMMSC‐CM + vitamin C
Secondary outcome: acceptability of treatment · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane
no estimate extractedNRNo studies
Topical timolol vs placebo
Proportion of parents who consider their child still has a problem, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Topical timolol vs placebo
Proportion of children who consider they still have a problem, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Topical timolol vs placebo
Aesthetic appearance as assessed by physician, child, or parent, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs topical timolol
Clearance, as assessed by a clinician at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs topical timolol
A subjective measure of improvement, as assessed by the parent or child, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs topical timolol
Proportion of parents who consider their child still has a problem, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs placebo
A subjective measure of improvement, as assessed by the parent or child, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs topical timolol
Proportion of children who consider they still have a problem, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs topical timolol
Aesthetic appearance as assessed by physician, child, or parent, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs placebo
Proportion of parents who consider their child still has a problem, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs placebo
Proportion of children who consider they still have a problem, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Oral propranolol vs placebo
Aesthetic appearance as assessed by physician, child, or parent, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Topical timolol vs placebo
Clearance, as assessed by a clinician at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Topical timolol vs placebo
A subjective measure of improvement, as assessed by the parent or child, at any · infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infantile haemangiomas of the skin (2018) · Cochrane
no estimate extractedNRNo studies
Anti‐CTLA4 monoclonal antibodies with vs without anti‐PD1 monoclonal antibodies
Overall survival · people with cutaneous melanoma
Systemic treatments for metastatic cutaneous melanoma (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs conventional treatment
Requirement for corticosteroid (steroid‐sparingeffect) · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs conventional treatment
Reduction of pruritus · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs conventional treatment
Improvement in quality of life · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs conventional treatment
Need for emollient use · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs placebo
Effect of long‐term control (> 3 months) · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs placebo
Improvement in quality of life · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs placebo
Need for emollient use · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Montelukast vs conventional treatment
Effect of long‐term control (> 3 months) · eczema
Leukotriene receptor antagonists for eczema (2018) · Cochrane
no estimate extractedNRNo studies
Intravenous immunoglobulin vs placebo
Assessment of long‐term morbidity · NSTI
Interventions for necrotizing soft tissue infections in adults (2018) · Cochrane
no estimate extractedNRNo studies
Moxifloxacin vs amoxicillin‐clavulanate
Assessment of long‐term morbidity · NSTI
Interventions for necrotizing soft tissue infections in adults (2018) · Cochrane
no estimate extractedNRNo studies
AB103 vs placebo
Survival time · NSTI
Interventions for necrotizing soft tissue infections in adults (2018) · Cochrane
no estimate extractedNRNo studies
AB103 vs placebo
Assessment of long‐term morbidity · NSTI
Interventions for necrotizing soft tissue infections in adults (2018) · Cochrane
no estimate extractedNRNo studies
Pimecrolimus 1% vs betamethasone 17‐valerate 0.1%
At least 50% reduction in erythema · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Pimecrolimus 1% vs betamethasone 17‐valerate 0.1%
Quality of life measure · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Pimecrolimus 1% vs betamethasone 17‐valerate 0.1%
Relapse · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Pimecrolimus 1% vs betamethasone 17‐valerate 0.1%
Adverse events of medication, leading to discontinuation or significant morbidity · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
R‐salbutamol 0.5% topical cream vs placebo
Quality of life measure · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
R‐salbutamol 0.5% topical cream vs placebo
Relapse · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Fluocinonide 0.05% vs hydrocortisone 1%
At least 50% reduction in erythema · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Tacrolimus 0.1% cream vs placebo
Clearing or excellent improvement · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Tacrolimus 0.1% cream vs placebo
At least 50% reduction in erythema · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Tacrolimus 0.1% cream vs placebo
Quality of life measure · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Tacrolimus 0.1% cream vs placebo
Relapse · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Fluocinonide 0.05% vs hydrocortisone 1%
Quality of life measure · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Fluocinonide 0.05% vs hydrocortisone 1%
Relapse · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies
Acitretin 50 mg daily vs hydroxychloroquine 400 mg daily
Quality of life measure · people with discoid lupus erythematosus
Drugs for discoid lupus erythematosus (2017) · Cochrane
no estimate extractedNRNo studies