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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Conjugated oral oestrogens vs transdermal 17ß‐estradiol
Endometrial thickness · girls with Turner syndrome who were treated with prepubertal growth hormone
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Oral vs vaginal administration of oestradiol and dydrogesterone
Reproductive outcomes · women with premature ovarian insufficiency (POI) awaiting oocyte donation
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Oral vs vaginal administration of oestradiol and dydrogesterone
Adverse events · women with premature ovarian insufficiency (POI) awaiting oocyte donation
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Conjugated oral oestrogens vs transdermal 17ß‐estradiol
Endometrial histology · girls with Turner syndrome who were treated with prepubertal growth hormone
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Conjugated oral oestrogens vs transdermal 17ß‐estradiol
Uterine perfusion · girls with Turner syndrome who were treated with prepubertal growth hormone
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Conjugated oral oestrogens vs transdermal 17ß‐estradiol
Reproductive outcomes · girls with Turner syndrome who were treated with prepubertal growth hormone
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Conjugated oral oestrogens vs transdermal 17ß‐estradiol
Adverse events · girls with Turner syndrome who were treated with prepubertal growth hormone
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Low vs high 17ß‐oestradiol dose
Endometrial thickness · young women with Turner syndrome who have completed pubertal induction
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics only
Need for additional IV or oral antibiotics · children and adults with pulmonary exacerbation in CF
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Inhaled antibiotics vs IV antibiotics
Time off work or school · children and adults with CF and an acute exacerbation
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics only
Time off work or school · children and adults with pulmonary exacerbation in CF
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control
Angiographic analysis · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard…
Local intramuscular transplantation of autologous bone marrow mononuclear cells for critical lower limb… (2022) · Cochrane
no estimate extractedNRNo studies
175 mg/m2 paclitaxel vs 250 mg/m2 paclitaxel
Quality of Life ‐ not measured · women with recurrent epithelial ovarian cancer
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer (2022) · Cochrane
no estimate extractedNRNo studies
175 mg/m2 paclitaxel vs 250 mg/m2 paclitaxel
Alopecia ‐ not reported · women with recurrent epithelial ovarian cancer
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer (2022) · Cochrane
no estimate extractedNRNo studies
135 mg/m2 paclitaxel vs 175 mg/m2 paclitaxel
Quality of Life ‐ not measured · women with recurrent epithelial ovarian cancer
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer (2022) · Cochrane
no estimate extractedNRNo studies
135 mg/m2 paclitaxel vs 175 mg/m2 paclitaxel
Neutropenia ‐ not reported · women with recurrent epithelial ovarian cancer
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer (2022) · Cochrane
no estimate extractedNRNo studies
135 mg/m2 paclitaxel vs 175 mg/m2 paclitaxel
Alopecia ‐ not measured · women with recurrent epithelial ovarian cancer
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer (2022) · Cochrane
no estimate extractedNRNo studies
Weekly paclitaxel vs three‐weekly paclitaxel
Quality of Life ‐ not reported · women with recurrent epithelial ovarian cancer
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs placebo
Gambling expenditure ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs placebo
Gambling frequency ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs placebo
Time spent gambling ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Atypical antipsychotics vs placebo
Functional impairment ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs opioid antagonists
Gambling expenditure ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs opioid antagonists
Gambling frequency ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs opioid antagonists
Time spent gambling ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs opioid antagonists
Functional impairment ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs mood stabilisers
Gambling expenditure ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs mood stabilisers
Gambling frequency ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs mood stabilisers
Time spent gambling ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs mood stabilisers
Functional impairment ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs mood stabilisers
Gambling symptom severity ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs mood stabilisers
Gambling expenditure ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs mood stabilisers
Gambling frequency ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs mood stabilisers
Time spent gambling ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs mood stabilisers
Functional impairment ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Opioid antagonists vs mood stabilisers
Responder status ‐ not measured · treatment of disordered and problem gambling
Pharmacological interventions for the treatment of disordered and problem gambling (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ Recurrence during · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ Long‐term complications during · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ All‐cause mortality · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ Adverse events · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Primary ‐ Short‐term complications (abscess, perforation, obstruction or fistula) within 30 days · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Primary ‐ Short‐term emergency surgery within 30 days · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ Recurrence during · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ All cause mortality · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary ‐ Adverse events · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Primary ‐ Short‐term complications (abscess, perforation, obstruction or fistula) within 30 days · Patients with acute uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis (2022) · Cochrane
no estimate extractedNRNo studies
Supportive and counselling interventions vs treatment
Depression remission post‐treatment · depression and anxiety for people with dementia
Psychological treatments for depression and anxiety in dementia and mild cognitive impairment (2022) · Cochrane
no estimate extractedNRNo studies
Brief admission to psychiatric hospital by self‐referral plus treatment as usual vs treatment
Quality of life · adults meeting 3 or more diagnostic criteria for borderline personality disorder
Crisis interventions for adults with borderline personality disorder (2022) · Cochrane
no estimate extractedNRNo studies