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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Adverse events resulting from DUS surveillance · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Functional walking ability · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Clinical severity scales · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
Limb salvage rate · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Weekly educational texts messages vs once every other week educational text messages
Flare‐ups or relapse (continuous) · people with inflammatory bowel disease
Patient education interventions for the management of inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Weekly educational texts messages vs once every other week educational text messages
Flare‐ups or relapse (dichotomous) · people with inflammatory bowel disease
Patient education interventions for the management of inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Web‐based patient education vs other delivery of patient education
Flare‐ups or relapse (continuous) · people with inflammatory bowel disease
Patient education interventions for the management of inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
Web‐based patient education vs other delivery of patient education
Flare‐ups or relapse (dichotomous) · people with inflammatory bowel disease
Patient education interventions for the management of inflammatory bowel disease (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Major neurodevelopmental disability in children aged 18 to 24 months CA · preterm infants at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Mortality or major neurodevelopmental disability in children aged 18 to 24 months and 3 to 5 years CA · preterm infants at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Side effects (tachycardia, agitation, or feed intolerance) leading to a reduction in dose or withholding of caffeine · preterm infants at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Seizures (clinically diagnosed; diagnosed by electroencephalography) · preterm infants at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Major neurodevelopmental disability in children aged 18 to 24 months CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Major neurodevelopmental disability in children aged 3 to 5 years CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Major neurodevelopmental disability in children aged 18 to 24 months CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Mortality or major neurodevelopmental disability in children aged 18 to 24 months and 3 to 5 years CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Duration of hospital stay (days) · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Seizures (clinically diagnosed; diagnosed by electroencephalography) · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Major neurodevelopmental disability in children aged 18 to 24 months CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Major neurodevelopmental disability in children aged 3 to 5 years CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Mortality or major neurodevelopmental disability in children aged 18 to 24 months and 3 to 5 years CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Side effects (tachycardia, agitation, or feed intolerance) leading to a reduction in dose or withholding of caffeine · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Duration of hospital stay (days) · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Seizures (clinically diagnosed; diagnosed by electroencephalography) · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
High‐dose vs standard‐dose strategies
Mortality or major neurodevelopmental disability in children aged 18 to 24 months and 3 to 5 years CA · preterm infants with or at risk for apnea of prematurity
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs non‐silicone gel sheeting treatment
Adherence to treatment · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs non‐silicone gel sheeting treatment
Health‐related quality of life · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs intralesional injections of triamcinolone acetonide
Scar severity validated by participants · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs intralesional injections of triamcinolone acetonide
Adverse events · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs intralesional injections of triamcinolone acetonide
Adherence to treatment · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs intralesional injections of triamcinolone acetonide
Health‐related quality of life · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no treatment
Scar severity validated by participants · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no treatment
Adverse events · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no treatment
Adherence to treatment · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no treatment
Health‐related quality of life · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs non‐silicone gel sheeting treatment
Scar severity validated by participants · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs non‐silicone gel sheeting treatment
Adverse events · people with keloid scars
Silicone gel sheeting for treating keloid scars (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
Clinical improvement D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
WHO progression score (level 7 or above) D28 ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
All‐cause mortality D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
Adverse events ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Siltuximab vs standard care/placebo
Clinical improvement D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Siltuximab vs standard care/placebo
Adverse events ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Levilimab vs standard care/placebo
Clinical improvement D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Levilimab vs standard care/placebo
WHO progression score (level 7 or above) D28 ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone
Mortality · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
Surgery for nasal polyposis in cystic fibrosis (2023) · Cochrane
no estimate extractedNRNo studies
Doxapram vs no treatment, placebo, methylxanthine (including theophylline, aminophylline, or caffeine), or
4a.Death at any time during initial hospitalization – doxapram compared to no treatment for the treatment of apnea · treatment of apnea
Doxapram for the prevention and treatment of apnea in preterm infants (2023) · Cochrane
no estimate extractedNRNo studies
Doxapram vs no treatment, placebo, methylxanthine (including theophylline, aminophylline, or caffeine), or
4b. Death at any time during initial hospitalization – doxapram compared to alternative treatment for the treatment of apnea · treatment of apnea
Doxapram for the prevention and treatment of apnea in preterm infants (2023) · Cochrane
no estimate extractedNRNo studies
Doxapram vs no treatment, placebo, methylxanthine (including theophylline, aminophylline, or caffeine), or
4c. Death at any time during initial hospitalization – doxapram as an adjunct to methylxanthine compared to methylxanthine alone for the treatment of apnea · treatment of apnea
Doxapram for the prevention and treatment of apnea in preterm infants (2023) · Cochrane
no estimate extractedNRNo studies
Doxapram vs no treatment, placebo, methylxanthine (including theophylline, aminophylline, or caffeine), or
5a. Moderate‐to‐severe neurodevelopmental disability or intellectual impairment after 2 years of age – doxapram compared to no treatment for the treatment of apnea · treatment of apnea
Doxapram for the prevention and treatment of apnea in preterm infants (2023) · Cochrane
no estimate extractedNRNo studies