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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

302 questions in 48 reviews · Neuromuscular

current versions
No studies 302 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Strength training vs no training
Quality of life · people with facioscapulohumeral muscular dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Strength training vs no training
Experienced fatigue · people with facioscapulohumeral muscular dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise vs no training
Muscle strength · people with dermatomyositis and polymyositis
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise vs no training
Quality of life · people with dermatomyositis and polymyositis
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise vs no training
Pain · people with dermatomyositis and polymyositis
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Strength training vs no training
Aerobic capacity · people with myotonic dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise vs no training
Experienced fatigue · people with dermatomyositis and polymyositis
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise vs no training
Quality of life · boys with DMD
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise vs no training
Pain · boys with DMD
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise vs no training
Experienced fatigue · boys with DMD
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Time‐scored functional assessments of muscle performance · people with mitochondrial myopathy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Strength training vs no training
Quality of life · people with myotonic dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Pain · people with mitochondrial myopathy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Experienced fatigue · people with mitochondrial myopathy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Muscle strength · people with myotonic dystrophy type 1
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Aerobic capacity · people with myotonic dystrophy type 1
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Quality of life · people with myotonic dystrophy type 1
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Pain · people with myotonic dystrophy type 1
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Experienced fatigue · people with myotonic dystrophy type 1
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Strength training vs no training
Pain · people with myotonic dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Pain · people with dermatomyositis and polymyositis
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Experienced fatigue · people with dermatomyositis and polymyositis
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Strength training vs no training
Experienced fatigue · people with myotonic dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Aerobic exercise and strength training vs no training
Pain · people with facioscapulohumeral muscular dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Strength training vs no training
Aerobic capacity · people with facioscapulohumeral muscular dystrophy
Strength training and aerobic exercise training for muscle disease (2019) · Cochrane
no estimate extractedNRNo studies
Riluzole vs placebo
Acquisition of the ability to stand · children with SMA type I
Drug treatment for spinal muscular atrophy type I (2019) · Cochrane
no estimate extractedNRNo studies
Riluzole vs placebo
Change in motor disability score · children with SMA type I
Drug treatment for spinal muscular atrophy type I (2019) · Cochrane
no estimate extractedNRNo studies
Riluzole vs placebo
Acquisition of head control · children with SMA type I
Drug treatment for spinal muscular atrophy type I (2019) · Cochrane
no estimate extractedNRNo studies
Acetyl‐L‐carnitine vs methylcobalamin
Impairment of sensation: quantitative sensory testing ‐ thermal threshold ‐ at 6 months or more · the treatment of diabetic peripheral neuropathy
Acetyl‐L‐carnitine for the treatment of diabetic peripheral neuropathy (2019) · Cochrane
no estimate extractedNRNo studies
Acetyl‐L‐carnitine vs placebo
Functional impairment and disability Assessed by NIS or NDS at 6 months or more · people with diabetic peripheral neuropathy
Acetyl‐L‐carnitine for the treatment of diabetic peripheral neuropathy (2019) · Cochrane
no estimate extractedNRNo studies
Acetyl‐L‐carnitine vs placebo
Impairment of sensation Assessed by quantitative sensory testing ‐ thermal threshold ‐ at 6 months or more · people with diabetic peripheral neuropathy
Acetyl‐L‐carnitine for the treatment of diabetic peripheral neuropathy (2019) · Cochrane
no estimate extractedNRNo studies
Acetyl‐L‐carnitine vs methylcobalamin
Pain at 6 months or more · the treatment of diabetic peripheral neuropathy
Acetyl‐L‐carnitine for the treatment of diabetic peripheral neuropathy (2019) · Cochrane
no estimate extractedNRNo studies
Acetyl‐L‐carnitine vs methylcobalamin
Impairment of sensation: quantitative sensory testing ‐ vibration perception threshold ‐ at 6 months or more · the treatment of diabetic peripheral neuropathy
Acetyl‐L‐carnitine for the treatment of diabetic peripheral neuropathy (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs sham training
Measures of lung capacity over the long term (greater than 1 year) · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs sham training
Physical function in carrying out activities of daily living · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs sham training
Quality of life · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs sham training
Number of unscheduled hospitalizations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs sham training
All adverse events · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs no training
Measures of lung capacity over the short term (less than 3 months) · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs no training
Measures of lung capacity over the long term (greater than 1 year) · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs no training
Physical function in carrying out activities of daily living · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs no training
Quality of life · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs no training
Number of unscheduled hospitalizations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs no training
All adverse events · children and young males with DMD
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs breathing exercises
Measures of lung capacity over the medium term (greater than 3 months but less than 1 year) · participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs breathing exercises
Measures of lung capacity over the long term (greater than 1 year) · participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs breathing exercises
Physical function in carrying out activities of daily living · participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs breathing exercises
Quality of life · participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs breathing exercises
Number of unscheduled hospitalisations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization · participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies
Respiratory muscle training vs breathing exercises
All adverse events · participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy
Respiratory muscle training in children and adults with neuromuscular disease (2019) · Cochrane
no estimate extractedNRNo studies