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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
555 questions in 79 reviews · Musculoskeletal
current versionsNo studies 555 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Vitamin C vs allopurinol Joint pain reduction · peoeple with chronic gout and sUA level > 0.36 mmol/L Dietary supplements for chronic gout (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs allopurinol Participant global assessment · peoeple with chronic gout and sUA level > 0.36 mmol/L Dietary supplements for chronic gout (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs allopurinol Tophus regression · peoeple with chronic gout and sUA level > 0.36 mmol/L Dietary supplements for chronic gout (2021) · Cochrane | no estimate extracted | NR | No studies |
Skim milk enriched with GMP/G600 vs skim milk, plus lactose powder Participant global assessment 5‐point Likert scale (5 = excellent) · people with chronic gout Dietary supplements for chronic gout (2021) · Cochrane | no estimate extracted | NR | No studies |
Skim milk enriched with GMP/G600 vs skim milk, plus lactose powder Tophus regression · people with chronic gout Dietary supplements for chronic gout (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs allopurinol Acute gout flares · peoeple with chronic gout and sUA level > 0.36 mmol/L Dietary supplements for chronic gout (2021) · Cochrane | no estimate extracted | NR | No studies |
Kinesiotaping vs other conservative treatment Global assessment of treatment success№ of participants: (0 studies) · rotator cuff disease Kinesio taping for rotator cuff disease (2021) · Cochrane | no estimate extracted | NR | No studies |
Kinesiotaping vs sham taping Global assessment of treatment success№ of participants: (0 studies) · rotator cuff disease Kinesio taping for rotator cuff disease (2021) · Cochrane | no estimate extracted | NR | No studies |
Kinesiotaping vs sham taping Quality of life№ of participants: (0 studies) · rotator cuff disease Kinesio taping for rotator cuff disease (2021) · Cochrane | no estimate extracted | NR | No studies |
Infliximab vs rituximab Disease flare/relapse · adults (age 18 years and older) with refractory GPA ANCA‐associated vasculitis Anti‐cytokine targeted therapies for ANCA‐associated vasculitis (2020) · Cochrane | no estimate extracted | NR | No studies |
Infliximab vs rituximab Any adverse event · adults (age 18 years and older) with refractory GPA ANCA‐associated vasculitis Anti‐cytokine targeted therapies for ANCA‐associated vasculitis (2020) · Cochrane | no estimate extracted | NR | No studies |
Mepolizumab vs placebo Disease flares · adults (age 18 years and older) with EGPA ANCA‐associated vasculitis Anti‐cytokine targeted therapies for ANCA‐associated vasculitis (2020) · Cochrane | no estimate extracted | NR | No studies |
Shock wave therapy vs placebo Quality of life · rotator cuff disease with or without calcification Shock wave therapy for rotator cuff disease with or without calcification (2020) · Cochrane | no estimate extracted | NR | No studies |
Knee replacement with tourniquet vs knee replacement without tourniquet Cognitive function Tourniquet use for knee replacement surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Participant‐rated global assessment of treatment success · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative… Shoulder replacement surgery for osteoarthritis and rotator cuff tear arthropathy (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Radiographic progression · people with rheumatoid arthritis Tai Chi for rheumatoid arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Short‐term serious adverse events · people with rheumatoid arthritis Tai Chi for rheumatoid arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Long‐term adverse effects or toxicity · people with rheumatoid arthritis Tai Chi for rheumatoid arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs placebo Outcomesa · osteoarthritis of the hip or knee, or both Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs acetaminophen Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs acetaminophen Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs acetaminophen Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs acetaminophen Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs NSAIDs Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs other opioids Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs NSAIDs Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs NSAIDs Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs placebo Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Anti‐TNF discontinuation vs anti‐TNF continuation Proportion participants that switched to another biologic due to loss of response ‐ not measured · people with rheumatoid arthritis with low disease activity using a standard dose of anti‐TNF agents Down‐titration and discontinuation strategies of tumour necrosis factor–blocking agents for rheumatoid… (2019) · Cochrane | no estimate extracted | NR | No studies |
Anti‐TNF disease activity–guided dose tapering vs anti‐TNF continuation Withdrawals due to adverse events ‐ not measured · people with rheumatoid arthritis with low disease activity using a standard dose of anti‐TNF agents Down‐titration and discontinuation strategies of tumour necrosis factor–blocking agents for rheumatoid… (2019) · Cochrane | no estimate extracted | NR | No studies |
Surgical intervention vs non‐surgical intervention Quality of life · Adults with symptomatic mild to moderate knee osteoarthritis defined as knee pain and radiographic evidence of non‐end… Surgical interventions for symptomatic mild to moderate knee osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs other DMARDs Health‐related quality of life ‐ not measured · psoriatic arthritis Methotrexate for psoriatic arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs other DMARDs Disease activity ‐ not measured · psoriatic arthritis Methotrexate for psoriatic arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs other DMARDs Radiographic progression ‐ not measured · psoriatic arthritis Methotrexate for psoriatic arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs placebo Health‐related quality of life ‐ not reported · psoriatic arthritis Methotrexate for psoriatic arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs placebo Radiographic progression ‐ not measured · psoriatic arthritis Methotrexate for psoriatic arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Arthroscopic surgery vs sclerosing injection Quality of life · adult participants with patellar tendinopathy Surgery for patellar tendinopathy (jumper’s knee) (2019) · Cochrane | no estimate extracted | NR | No studies |
Arthroscopic surgery vs sclerosing injection Adverse event · adult participants with patellar tendinopathy Surgery for patellar tendinopathy (jumper’s knee) (2019) · Cochrane | no estimate extracted | NR | No studies |
Arthroscopic surgery vs sclerosing injection Tendon rupture · adult participants with patellar tendinopathy Surgery for patellar tendinopathy (jumper’s knee) (2019) · Cochrane | no estimate extracted | NR | No studies |
Open surgical excision vs eccentric exercises Quality of life · adult participants with patellar tendinopathy Surgery for patellar tendinopathy (jumper’s knee) (2019) · Cochrane | no estimate extracted | NR | No studies |
Open surgical excision vs eccentric exercises Tendon rupture · adult participants with patellar tendinopathy Surgery for patellar tendinopathy (jumper’s knee) (2019) · Cochrane | no estimate extracted | NR | No studies |
Arthroscopic surgery vs sclerosing injection Function · adult participants with patellar tendinopathy Surgery for patellar tendinopathy (jumper’s knee) (2019) · Cochrane | no estimate extracted | NR | No studies |
Paracetamol vs placebo Quality of life Not measured · people with hip or knee osteoarthritis Paracetamol versus placebo for knee and hip osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Percutaneous surgery vs steroid injection Function Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Percutaneous surgery vs steroid injection Participant global assessment of success Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |