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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Oestrogen cream vs other regimens
Endometrial thickness not reported · postmenopausal women with vaginal atrophy
Local oestrogen for vaginal atrophy in postmenopausal women (2016) · Cochrane
no estimate extractedNRNo studies
Healthcare professional‐led breastfeeding education and support vs standard care
Early initiation of breastfeeding · women exposed to interventions intended to promote breastfeeding
Interventions for promoting the initiation of breastfeeding (2016) · Cochrane
no estimate extractedNRNo studies
Multinutrient supplements (nasogastric) vs control
Unfavourable outcome · Older people undergoing hip fracture aftercare
Nutritional supplementation for hip fracture aftercare in older people (2016) · Cochrane
no estimate extractedNRNo studies
Multinutrient supplements (nasogastric) vs control
Putative side effects of treatment (e.g. aspiration pneumonia) · Older people undergoing hip fracture aftercare
Nutritional supplementation for hip fracture aftercare in older people (2016) · Cochrane
no estimate extractedNRNo studies
Dietary supplements vs placebo
Outcomes1 · women with moderate or severe primary dysmenorrhoea
Dietary supplements for dysmenorrhoea (2016) · Cochrane
no estimate extractedNRNo studies
Antibiotic vs no treatment
Size of lesion · People with toxoplasma retinochoroiditis
Antibiotics versus no treatment for toxoplasma retinochoroiditis (2016) · Cochrane
no estimate extractedNRNo studies
Antioestrogen vs placebo
Live birth rate ‐ not reported · ovulation induction in polycystic ovarian syndrome
Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome (2016) · Cochrane
no estimate extractedNRNo studies
Antioestrogen vs placebo
Miscarriage rate ‐ not reported · ovulation induction in polycystic ovarian syndrome
Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome (2016) · Cochrane
no estimate extractedNRNo studies
Antioestrogen vs placebo
Multiple pregnancy rate ‐ not reported · ovulation induction in polycystic ovarian syndrome
Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome (2016) · Cochrane
no estimate extractedNRNo studies
Antioestrogen vs placebo
Ovarian hyperstimulation syndrome (OHSS) ‐ not reported · ovulation induction in polycystic ovarian syndrome
Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome (2016) · Cochrane
no estimate extractedNRNo studies
Protocol using standard measures such as CVP vs usual care
Return to pre‐fracture accommodation/return to pre‐fracture mobility · patients with perioperative fluid optimization
Perioperative fluid volume optimization following proximal femoral fracture (2016) · Cochrane
no estimate extractedNRNo studies
Advanced haemodynamic monitoring vs protocol using standard measures such
Return to pre‐fracture accommodation/return to pre‐fracture mobility · patients with proximal femoral fracture
Perioperative fluid volume optimization following proximal femoral fracture (2016) · Cochrane
no estimate extractedNRNo studies
Lactulose vs lactitol
Quality of life (secondary outcome) · prevention and treatment of hepatic encephalopathy in people with cirrhosis
Non‐absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention… (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs exposed wound
SSI Assessment method: clinical features of infection · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Silver dressing vs exposed wound
Scarring · surgical wounds resulting from surgery at risk of contamination and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Silver dressing vs exposed wound
Acceptability · surgical wounds resulting from surgery at risk of contamination and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Silver dressing vs exposed wound
Ease of dressing removal · surgical wounds resulting from surgery at risk of contamination and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
SSI Assessment method: various methods · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
Scarring · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
Acceptability of dressing to participant Clean surgery Assessment method:VAS, participants rated dressing acceptability (0 = no trouble and 10 = very troublesome) · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
Ease of dressing removal Assessment method: unclear · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
SSIClean surgery Assessment method: CDC definition of SSI · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
Scarring Clean surgery Assessment method: participants assessed different aspects of scarring as either: excellent, good or fair · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
Acceptability of dressing to participant Clean surgery Assessment method: participants rated whether they were dissatisfied with the dressing · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs exposed wound
Scarring (further information not reported) · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
Ease of dressing removal Clean surgery Assessment method: questions regarding dressing removal · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs fibrous‐hydrocolloid dressing
Acceptability of dressing to participant · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs fibrous‐hydrocolloid dressing
Ease of dressing removal · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs polyurethane matrix hydrocolloid dressings
SSI · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs polyurethane matrix hydrocolloid dressings
Scarring · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs polyurethane matrix hydrocolloid dressings
Acceptability of dressing to participant · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs silver dressing
SSI potentially contaminated surgery SSI Assessment method: various clinical measures · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs exposed wound
Acceptability of dressing to participant Clean surgery Assessment method: VAS · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs silver dressing
Scarring · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs silver dressing
Acceptability of dressing to participant · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs silver dressing
Ease of dressing removal · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
SSI Assessment method: CDC definition of SSI · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
Scarring · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
Acceptability of dressing to participant · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
Ease of dressing removal · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs exposed wound
Ease of dressing removal · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Film dressing vs exposed wound
Ease of dressing removal · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as add‐on therapy vs placebo
Efficacy: change in scores from baseline to endpoint on symptom rating scales in the treatment of depressive episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as add‐on therapy vs placebo
Response to treatment with topiramate. Number of participants experiencing a 50% reduction or greater in mean score from baseline to end of treatment on symptom rating scales in depressive episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as add‐on therapy vs placebo
Remission with topiramate. Number of participants presenting with a rating scale score within the normal range at the endpoint in manic and mixed episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as add‐on therapy vs placebo
Remission with topiramate. Number of participants presenting with a rating scale score within the normal range at the endpoint in depressive episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as monotherapy vs an alternative drug
Efficacy: change in scores from baseline to endpoint on symptom rating scales in the treatment of depressive episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as monotherapy vs an alternative drug
Response to treatment with topiramate. Number of participants experiencing a 50% reduction or greater in mean score from baseline to end of treatment on symptom rating scales in manic and mixed episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as monotherapy vs an alternative drug
Response to treatment with topiramate. Number of participants experiencing a 50% reduction or greater in mean score from baseline to end of treatment on symptom rating scales in depressive episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topiramate as monotherapy vs an alternative drug
Remission with topiramate. Number of participants presenting with a rating scale score within the normal range at the endpoint in manic and mixed episodes · adults with acute affective episodes in bipolar disorder
Topiramate for acute affective episodes in bipolar disorder in adults (2016) · Cochrane
no estimate extractedNRNo studies