Cochrane · systematic review · CD001880

Nutritional supplementation for hip fracture aftercare in older people

Avenell, A, Smith, TO, Curtain, JP, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Bone, Joint and Muscle TraumaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
6
No studies
2
Included studies
NR
No studies 2 · 25%Ungraded 0 · 0%Very low 4 · 50%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Multinutrient supplements (oral) versus control for hip fracture aftercare in older people

Population: Older people undergoing hip fracture aftercare
4 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality by end of study
Multinutrient supplements (oral) vs control
RR 0.81 [0.49, 1.31]15 studies · 968 participantsLow
Downgraded: risk of bias, imprecision
Participants with complications (e.g. pressure sore, chest infection) at end of study
Multinutrient supplements (oral) vs control
RR 0.71 [0.59, 0.86]11 studies · 727 participantsLow
Downgraded: risk of bias
Unfavourable outcome 7 by end of study
Multinutrient supplements (oral) vs control
RR 0.67 [0.51, 0.89]6 studies · 334 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Putative side effects of treatment (e.g. vomiting and diarrhoea)
Multinutrient supplements (oral) vs control
RR 0.99 [0.47, 2.05]6 studies · 442 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness

Multinutrient supplements (nasogastric) versus control for hip fracture aftercare in older people

Population: Older people undergoing hip fracture aftercare
4 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality by end of study
Multinutrient supplements (nasogastric) vs control
RR 0.99 [0.5, 1.97]3 studies · 280 participantsVery low
Downgraded: risk of bias, inconsistency
Participants with complications (e.g. pressure sore, aspiration pneumonia) at end of study
Multinutrient supplements (nasogastric) vs control
RR 1.09 [0.73, 1.64]1 study · 18 participantsVery low
Downgraded: risk of bias, imprecision
Unfavourable outcome
Multinutrient supplements (nasogastric) vs control
no estimate extractedNRNo studies
Putative side effects of treatment (e.g. aspiration pneumonia)
Multinutrient supplements (nasogastric) vs control
no estimate extractedNRNo studies