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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
132 questions in 24 reviews · Acute Respiratory Infections
current versionsNo studies 132 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Positive expiratory pressure plus routine treatment vs routine treatment alone Duration of ICU stay ‐ not reported · people with pneumonia Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Positive expiratory pressure plus routine treatment vs routine treatment alone Duration of mechanical ventilation ‐ not reported · people with pneumonia Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
High‐frequency chest wall oscillation plus fibrobronchoscope alveolar lavage vs fibrobronchoscope alveolar lavage alone Cure rate ‐ not reported · people with severe pneumonia and receiving mechanical ventilation Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
High‐frequency chest wall oscillation plus fibrobronchoscope alveolar lavage vs fibrobronchoscope alveolar lavage alone Duration of hospital stay ‐ not reported · people with severe pneumonia and receiving mechanical ventilation Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
High‐frequency chest wall oscillation plus fibrobronchoscope alveolar lavage vs fibrobronchoscope alveolar lavage alone Duration of fever ‐ not reported · people with severe pneumonia and receiving mechanical ventilation Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
High‐frequency chest wall oscillation plus fibrobronchoscope alveolar lavage vs fibrobronchoscope alveolar lavage alone Duration of total antibiotic therapy ‐ not reported · people with severe pneumonia and receiving mechanical ventilation Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Conventional chest physiotherapy plus routine treatment vs routine treatment alone Duration of total antibiotic therapy ‐ not reported · people with pneumonia Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Conventional chest physiotherapy plus routine treatment vs routine treatment alone Duration of ICU stay ‐ not reported · people with pneumonia Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Conventional chest physiotherapy plus routine treatment vs routine treatment alone Duration of mechanical ventilation ‐ not reported · people with pneumonia Chest physiotherapy for pneumonia in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Point‐of‐care biomarkers (procalcitonin) for infection vs standard of care Clinical recovery within 28 days · people with acute respiratory infections Biomarkers as point‐of‐care tests to guide prescription of antibiotics in people with acute respiratory… (2022) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs placebo or no treatment Change in heart rate at 60 minutes · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs placebo or no treatment Duration of hospitalisation · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs placebo or no treatment Proportion of children intubated · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs placebo or no treatment Duration of intubation · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs placebo or no treatment Adverse events · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs oxygen 30% Proportion of children hospitalised · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs oxygen 30% Duration of hospitalisation · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs oxygen 30% Proportion of children intubated · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs oxygen 30% Duration of intubation · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs oxygen 30% Proportion of children re‐presenting for medical care for ongoing croup symptoms · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Heliox vs oxygen 30% Adverse events · children with croup Heliox for croup in children (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs placebo Prevalance of pneumonia · school‐aged children (6 to 15 years) and marine corps recruits (mean age 18.5 years) Vitamin C supplementation for prevention and treatment of pneumonia (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs placebo Mortality due to pneumonia · school‐aged children (6 to 15 years) and marine corps recruits (mean age 18.5 years) Vitamin C supplementation for prevention and treatment of pneumonia (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs placebo Clinical cure rate · children under 5 years of age Vitamin C supplementation for prevention and treatment of pneumonia (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs placebo Mortality due to pneumonia · children under 5 years of age Vitamin C supplementation for prevention and treatment of pneumonia (2021) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs placebo Adverse effects · children under 5 years of age Vitamin C supplementation for prevention and treatment of pneumonia (2021) · Cochrane | no estimate extracted | NR | No studies |
Linezolid vs vancomycin Health‐related quality of life Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Linezolid vs vancomycin Pneumonia‐related mortality Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Linezolid vs vancomycin Non‐serious adverse events Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Cefepime vs ceftazidime Health‐related quality of life Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Cefepime vs ceftazidime Pneumonia‐related mortality Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Cefepime vs ceftazidime Non‐serious adverse events Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Linezolid vs vancomycin All‐cause mortality Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Linezolid vs vancomycin Serious adverse events Maximum · neonates and children with hospital‐acquired pneumonia Antibiotics for hospital‐acquired pneumonia in neonates and children (2021) · Cochrane | no estimate extracted | NR | No studies |
Pneumococcal conjugate vaccine vs control vaccine Adverse effects · infants (predominantly < 6 months of age) and older children (aged 1 to 7 years) Pneumococcal conjugate vaccines for preventing acute otitis media in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Test result · people of any age with suspected acute meningitis in the emergency settingPrior testing: clinical information would… Diagnostic test accuracy of jolt accentuation for headache in acute meningitis in the emergency setting (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR CI: confidence interval · people without consciousness disturbance of any age with suspected acute meningitis in the emergency settingPrior… Diagnostic test accuracy of jolt accentuation for headache in acute meningitis in the emergency setting (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR CI: confidence interval · people of any age with suspected acute meningitis in the emergency settingPrior testing: clinical information would… Diagnostic test accuracy of jolt accentuation for headache in acute meningitis in the emergency setting (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Test result · people without consciousness disturbance of any age with suspected acute meningitis in the emergency settingPrior… Diagnostic test accuracy of jolt accentuation for headache in acute meningitis in the emergency setting (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate vs placebo Time to recovery · children up to 18 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate vs hypertonic saline Adverse events · children up to 12 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate vs hypertonic saline Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured at 0 to 24 hoursafter treatment · children up to 12 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate vs hypertonic saline Hospital re‐admission within 30 days of discharge · children up to 12 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate or magnesium sulphate + salbutamol vs salbutamol Time to recovery · children from 1 month to 24 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate or magnesium sulphate + salbutamol vs salbutamol Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured at 0 to 24 hoursafter treatment · children from 1 month to 24 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate or magnesium sulphate + salbutamol vs salbutamol Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured 25 to 48 hoursafter treatment · children from 1 month to 24 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate or magnesium sulphate + salbutamol vs salbutamol Hospital re‐admission within 30 days of discharge · children from 1 month to 24 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine Time to recovery · children up to 12 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine Mortality · children up to 12 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |
Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine Adverse events · children up to 12 months old with acute bronchiolitis Magnesium sulphate for treating acute bronchiolitis in children up to two years of age (2020) · Cochrane | no estimate extracted | NR | No studies |