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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

21 questions in 2 reviews · cluster CL0336

current versions
No studies 0 · 0%Ungraded 21 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline
Future caries experience (dmft/dmfs) · Children younger than 6 years with caries-free primary dentition (no cavitated or non-cavitated lesions at baseline) · 1 to 2 years, Overall
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and… (2023)
SMD 0.85 [0.33, 1.37]4 studies · 1323 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFS (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Not adjusted
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.43 [0.04, 0.83]22 studies · 11300 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFT (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Not adjusted
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.18 [-0.04, 0.40]13 studies · 24753 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFT (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.06 to 0.7314 studies · 25206 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFT (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for bitewings and age at baseline
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.18 [0.02, 0.35]13 studies · 24753 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFS (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.07 to 1.7726 studies · 22803 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in dmfs (primary dentition) · Children (primary dentition, d3), Western or comparable populations · Per year of follow-up
Caries Progression Rates Revisited: A Systematic Review. (2019)
-1.0 to 1.07 studies · 5896 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFS (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for bitewings and age at baseline
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.64 [0.31, 0.96]22 studies · 11300 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFS (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for bitewings age at baseline and baseline caries experience
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.37 [0.04, 0.70]22 studies · 11300 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFS (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up, Baseline caries experience: moderate
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.23 to 1.2313 studies · 16473 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFT (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up, Baseline caries experience: high
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.391 study · 4380 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFT (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for bitewings age at baseline and baseline caries experience
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.23 [0.06, 0.40]13 studies · 24753 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFS (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for groups 1-4 including relevance of evidence and risk of bias
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.46 [0.08, 0.83]22 studies · 11300 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFT (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for groups 1-4 including relevance of evidence and risk of bias
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up -0.04 [-0.34, 0.26]13 studies · 24753 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFS (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for groups 1-3 including decade and preventive intervention
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.36 [-0.02, 0.73]22 studies · 11300 participantsUngraded
Longer follow-up vs Shorter follow-up
Annual increment in DMFT (D3) · Children and adolescents with permanent dentition · Per additional year of follow-up, Adjusted for groups 1-3 including decade and preventive intervention
Caries Progression Rates Revisited: A Systematic Review. (2019)
Meta-regression beta per year of follow-up 0.07 [-0.24, 0.39]13 studies · 24753 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFS (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up, Baseline caries experience: high
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.44 to 1.775 studies · 2595 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in dmft (primary dentition) · Children (primary dentition, d3), Western or comparable populations · Per year of follow-up
Caries Progression Rates Revisited: A Systematic Review. (2019)
-0.3 to 0.34 studies · 1734 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFT (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up, Baseline caries experience: low
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.06 to 0.347 studies · 4121 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFT (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up, Baseline caries experience: moderate
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.24 to 0.736 studies · 16705 participantsUngraded
Longitudinal follow-up over time (natural caries progression; no assigned intervention) vs Within-cohort change from baseline to follow-up (>=3 y)
Annual increment in DMFS (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations · Per year of follow-up, Baseline caries experience: low
Caries Progression Rates Revisited: A Systematic Review. (2019)
0.07 to 0.538 studies · 3735 participantsUngraded