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Evidence found and GRADE certainty

24 questions · 39 findings · 6 reviews · Endodontics and dental trauma · related questions CL0289

No studies found 0 · 0%GRADE not reported 31 · 79.5%Very low 2 · 5.1%Low 4 · 10.3%Moderate 2 · 5.1%High 0 · 0%

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Postoperative pain (patient-reported) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…

The effect of material choice (MTA vs CaOH) on postoperative pain is unclear: two small studies used different methods and reported contradictory results, so no meta-analysis was performed (ungraded).

1 finding from 1 review

Biodentine vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…

Biodentine and calcium hydroxide did not differ significantly in clinical and radiographic success (OR 3.14, 95% CI 0.91 to 10.86; ungraded subgroup analysis).

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…

Mineral trioxide aggregate shows higher odds of clinical and radiographic success than calcium hydroxide (OR 3.05, 95% CI 1.70 to 5.45; ungraded subgroup analysis).

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure

In partial pulpotomy, MTA had significantly higher success than calcium hydroxide (OR 2.81; ungraded).

5 findings from 2 reviews · compare the 2 reviews
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Platelet-rich fibrin (PRF) graft vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Mature permanent teeth with irreversible pulpitis and carious pulp exposure (treated with full pulpotomy)

Platelet-rich fibrin and calcium hydroxide showed no significant difference in success (ungraded; effect size not reported).

1 finding from 1 review

Tooth location

Pulp necrosis · Vital teeth

One study reported a 7.1% incidence in mandibular posterior teeth.

8 findings from 1 review
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Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy

The effect of MTA versus CH after pulpotomy is uncertain (low certainty).

1 finding from 1 review

Platelet-rich fibrin (PRF) graft vs Mineral trioxide aggregate (MTA)

Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth undergoing pulpotomy

The two trials of PRF versus MTA for success gave contradictory results and were not pooled (ungraded).

1 finding from 1 review

Pre-operative bone level < 35% vs Pre-operative bone level ≥ 35%

Periapical pathosis incidence · Vital teeth

One study reported a 1.4% incidence with bone level < 35%.

2 findings from 1 review

Eugenol-based temporary cement vs Eugenol-free temporary cement

Pulp necrosis · Vital teeth

The pooled incidence with eugenol-based temporary cement was 3.34%.

2 findings from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth

The effect of MTA versus CH in immature teeth is very uncertain (very low certainty).

1 finding from 1 review

Polyether impression material vs Polyvinyl siloxane impression material

Pulp necrosis · Vital teeth

The pooled incidence with polyether impression material was 4.02%.

2 findings from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing direct pulp capping

MTA increases clinical and radiographic success versus CH after direct pulp capping (moderate certainty).

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth with mixed root development

The effect of MTA versus CH in teeth with mixed root development is very uncertain (very low certainty).

1 finding from 1 review