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Evidence found and GRADE certainty

211 questions · 317 findings · 16 reviews · Periodontology · related questions CL0289

No studies found 44 · 13.9%GRADE not reported 184 · 58%Very low 59 · 18.6%Low 21 · 6.6%Moderate 5 · 1.6%High 4 · 1.3%

Routine scale and polish every 6 months vs Routine scale and polish every 12 months

Plaque · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

Routine scale and polish every 6 months showed no clear difference in plaque compared with routine scale and polish every 12 months (low certainty).

1 finding from 1 review

Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone

Clinical attachment level (CAL) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

Mechanical debridement plus local antimicrobial (minocycline… showed no clear difference in clinical attachment level (mm) compared with mechanical debridement alone (low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in probing depth (PD) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).

1 finding from 1 review

Routine scale and polish every 6 months vs Routine scale and polish every 12 months

Probing pocket depth · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

Routine scale and polish every 6 months showed no clear difference in probing depth compared with routine scale and polish every 12 months (high certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in radiographic bone defect filling (RBF) (%) compared with EMD (enamel matrix derivative) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review

SPT performed by non-specialist clinicians (general dental practitioners under specialist prescription) vs SPT performed by specialists (specialist practice)

Periodontitis (clinical attachment loss) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

The review found no eligible studies for this question.

1 finding from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) vs Open flap debridement (access flap surgery)

Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in radiographic bone defect filling (RBF) (%) compared with OFD (open flap debridement) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

The review found no eligible studies for this question.

1 finding from 1 review

Routine scale and polish every 6 months vs Routine scale and polish every 12 months

Participant satisfaction (perceived oral cleanliness) · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

It is very uncertain whether routine scale and polish every 6 months changes participant satisfaction (perceived oral cleanliness) compared with routine scale and polish every 12 months (very low certainty).

1 finding from 1 review

Routine scale and polish at a fixed interval vs No scheduled scale and polish treatment

Plaque · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

Planned, regular routine scale and polish (6-monthly; 12-monthly… showed no clear difference in plaque compared with no scheduled scale and polish treatment (low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) vs Open flap debridement (access flap surgery)

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in clinical attachment level (CAL) (mm) compared with OFD (open flap debridement) alone (very low certainty).

1 finding from 1 review

Routine scale and polish at a fixed interval vs No scheduled scale and polish treatment

Calculus · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

Planned, regular routine scale and polish (6-monthly; 12-monthly… leads to lower calculus compared with no scheduled scale and polish treatment (high certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) vs Open flap debridement (access flap surgery)

Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review

Routine scale and polish provided by a dentist vs Routine scale and polish provided by a dental care professional (dental therapist or hygienist)

Participant satisfaction · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Clinical attachment level (CAL) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… led to lower clinical attachment level compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review