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Evidence found and GRADE certainty

212 questions · 218 findings · 11 reviews · Temporomandibular disorders and sleep · related questions CL0289

No studies found 56 · 25.7%GRADE not reported 135 · 61.9%Very low 27 · 12.4%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Physiotherapy modalities (physiotherapy, short-wave diathermy, ultrasound)

Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

The review found no eligible studies for this question.

1 finding from 1 review

Oral diclofenac sodium (NSAID) vs splint

Pain (on movement and on palpation of the affected TMJ) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
1 finding from 1 review
  • Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
    1 week and 3 months
    Data for pain on movement or pain on palpation of the affected TMJ (both at 1 week and 3 months) could not be extracted, as they are described as percentages of an unclear total number. Narratively, diclofenac sodium…
    1 study
    GRADE not reported

Open TMJ surgery (arthroplasty / total joint replacement)

Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

The review found no eligible studies for this question.

1 finding from 1 review

Glucosamine sulfate (oral) vs ibuprofen

Pain during function (proportion without significant improvement) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Glucosamine sulfate (oral) led to lower pain during function (proportion without significant improvement) compared with ibuprofen (oral); GRADE not reported.

1 finding from 1 review
  • Six participants in the glucosamine group did not experience significant improvement in TMJ pain compared with seven in the ibuprofen group (Analysis 3.1); Fisher's exact test P = 0.73 (not significant, per the authors).
    1 study · 45 participants
    GRADE not reported

Arthroscopy vs open surgery

Tenderness on palpation in jaw muscles (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in tenderness on palpation in jaw muscles (clinical evaluation, 12… compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Tenderness on palpation in TMJ (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in tenderness on palpation in TMJ (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Maximum protrusion over 5 mm (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in maximum protrusion over 5 mm (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Interincisal opening over 35 mm (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in interincisal opening over 35 mm (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs Arthrocentesis

Maximal mouth opening (interincisal distance) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy led to higher maximum interincisal opening (mm) after 12 months compared with arthrocentesis; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Clinical evaluations 12 months after surgery (6 pooled clinical signs) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in clinical evaluations 12 months after surgery (6 pooled clinical signs) compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs Nonsurgical treatment

Pain after 6 months · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in pain after 6 months compared with nonsurgical treatment; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Pain (VAS/SSI) after 12 months · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy led to higher pain (VAS/SSI) after 12 months compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs Arthrocentesis

Pain (VAS) after 12 months · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in pain (VAS) after 12 months compared with arthrocentesis; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Crepitation (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in crepitation (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Click (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in click (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Mandibular functionality (MFIQ) after 12 months · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in mandibular functionality (MFIQ) after 12 months compared with open surgery; GRADE not reported.

1 finding from 1 review

Oral glucosamine hydrochloride/chondroitin sulphate vs placebo

Pain on TMJ palpation (ordinal scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in pain on TMJ palpation (ordinal scale) compared with placebo; GRADE not reported.

1 finding from 1 review

Oral propranolol vs placebo

Change in pain index · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Oral propranolol (beta-blocker) showed no clear difference in change in pain index compared with placebo; GRADE not reported.

1 finding from 1 review

Oral clonazepam (benzodiazepine) vs placebo

Participants' assessment of improvement of pain in right TMJ (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Oral clonazepam (benzodiazepine) showed no clear difference in participants' assessment of improvement of pain in right TMJ (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review