Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo)
Outcome not reported · People with Von Willebrand disease undergoing minor oral surgery or dental extractions
The review found no eligible studies for this question.
1 finding from 1 review
Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
The review found no eligible studies for this question.
1 finding from 1 review
Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Scaling and root planing (SRP) plus glycine powder air polishing showed no clear difference in volatile sulphur compounds (VSC), halimeter compared with scaling and root planing (SRP) alone; GRADE not reported.
1 finding from 1 review
Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
It is very uncertain whether hinokitiol gel changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with placebo gel (very low certainty).
1 finding from 1 review
Patient's family member-reported VAS score (scale 0 to 100) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1000 mg champignon extract showed no clear difference in patient's family member-reported VAS score (scale 0 to 100) compared with placebo; GRADE not reported.
1 finding from 1 review
Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
It is very uncertain whether hyperbaric oxygen therapy (HBO) following extractions changes incidence of ORN compared with perioperative antibiotic prophylaxis (penicillin G) following… (very low certainty).
1 finding from 1 review
Tooth survival · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether thymosin alpha 1 (10-minute soak prior to replantation) changes tooth survival at 12 months compared with control (saline) (very low certainty).
2 findings from 1 review
Reduction in gagging (patient-reported) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
It is very uncertain whether acupressure at P6 point with device plus sedation changes reduction in gagging (patient-reported) compared with sham (dummy) acupressure with sedation (very low certainty).
1 finding from 1 review
Aesthetics (discolouration) at 12 months (patient level) · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether ledermix root canal medicament (day 0 to 10) changes aesthetics (discolouration) at 12 months (patient level) compared with ultracal root canal medicament (day 7 to 10) (very low certainty).
1 finding from 1 review
Reduction in gagging (patient-reported) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
It is very uncertain whether acupressure at P6 point with thumb plus sedation changes reduction in gagging (patient-reported) compared with sham (dummy) acupressure with sedation (very low certainty).
1 finding from 1 review
Treatment with antibiotics vs No antibiotics, placebo, or different types of antibiotics
Outcome not reported · People with avulsed and replanted permanent (front) teeth
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Total number of ibuprofen tablets · Adults over 18 years presenting with a single tooth with a clinical diagnosis of irreversible pulpitis
Systemic antibiotic (oral penicillin 500 mg) plus analgesic showed no clear difference in total number of ibuprofen tablets compared with placebo plus analgesic (low certainty).
1 finding from 1 review
Pain · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Reduction in gagging (patient-reported) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
It is very uncertain whether acupuncture at P6 point changes reduction in gagging (patient-reported – ordinal converted to… compared with sham acupuncture (very low certainty).
2 findings from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found higher pulpotomy success with triple antibiotic paste than abscess remedy (100% vs 80%; statistically significant, P<0.05; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 TAP and 20 AR teeth): TAP 100% (20/20) vs abscess remedy 80% (16/20) clinical and radiographic success; difference statistically significant at 3, 6, 9, 12, 18 and 24 months (P<0.05);…
1 study · 40 participants
GRADE not reported
Change in haemoglobin level from baseline · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions
1 finding from 1 review
Mean fall in haemoglobin. Forbes (TXA): 1.4 g/100 mL (placebo) vs 0.3 g/100 mL (TXA). Walsh (EACA): 6.3% (placebo, both centres) vs 3.9% and 3.7% (EACA, centres 1 and 2); differences not significant. Reported in…
2 studies · 59 participants
GRADE not reported
Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
The review found no eligible studies for this question.
1 finding from 1 review
Plaque · Medically healthy individuals (adults and children, 6-60 years)
Placebo rinse did not significantly change plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Presence or absence of gagging · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
The review found no eligible studies for this question.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
It is very uncertain whether 1000 mg champignon extract changes patient-reported visual analogue scale (VAS) score (scale 0 to 100) compared with 50 mg champignon extract (very low certainty).
1 finding from 1 review