Food preference · Children and adolescents (general population, aged under 20 years)
In crossover studies with binary outcomes, food marketing increased food preference (OR 3.49, 95% CI 2.03 to 6.22; ungraded).
1 finding from 1 review
OR 3.49 [2.03, 6.22]
4 studies
GRADE not reported
Pulpal disease (signs/symptoms of pulp necrosis) · Children with dentine caries in primary and permanent teeth
The reported estimate did not show a clear difference in pulpal disease after partial versus complete caries removal (ungraded).
1 finding from 1 review
RR 0.27 [0.05, 1.60]
3 studies
GRADE not reported
Lactobacilli presence (CFU > 10^5) · Adults undergoing orthodontic treatment
Aligners probably lower the risk of high lactobacilli counts versus fixed appliances in adults at 3 months (RR 0.09, 95% CI 0.02 to 0.47; low certainty).
2 findings from 1 review
Average fluorescence loss (dF%) · Adults undergoing orthodontic treatment
A single study reported lower average fluorescence (mineral) loss with aligners versus fixed appliances in adults at 3 months (MD -1.40, 95% CI -2.15 to -0.65; ungraded).
1 finding from 1 review
MD -1.40 [-2.15, -0.65]
1 study
GRADE not reported
Plaque · Adolescents/teenagers undergoing orthodontic treatment
A single study reported a lower full-mouth plaque score with aligners versus fixed appliances in adolescents at 12 months (MD -43.48, 95% CI -47.65 to -39.31; ungraded).
1 finding from 1 review
Probing pocket depth (PPD/PD) · Adults undergoing orthodontic treatment
Aligners may reduce pocket depth compared with fixed appliances in adults at 6-12 weeks (MD -0.42 mm, 95% CI -0.71 to -0.12; very low certainty).
1 finding from 1 review
Lesion area (decalcification area, pixels) · Adults undergoing orthodontic treatment
A single study reported a larger decalcification lesion area with aligners versus fixed appliances in adults at 3 months (MD 80.50 pixels, 95% CI 60.52 to 100.48; ungraded).
1 finding from 1 review
MD 80.50 [60.52, 100.48]
1 study
GRADE not reported
Incidence of microleakage · Er,Cr:YSGG laser-prepared cavities restored with self-etch adhesive systems (in vitro)
At the dentin margin, prior acid etching with self-etch adhesives significantly reduced microleakage (RR 2.44, 95% CI 1.38-4.34; ungraded).
3 findings from 1 review
RR 2.44 [1.38, 4.34]
2 studies
GRADE not reported
RR 3.00 [1.54, 5.83]
2 studies
GRADE not reported
RR 2.69 [1.74, 4.15]
2 studies
GRADE not reported
Incidence of microleakage · Human teeth requiring cavity preparation and restoration (in vitro)
At the dentin margin, microleakage did not differ significantly between bur and Er,Cr:YSGG laser preparation (RR 1.26, 95% CI 0.67-2.38; ungraded).
4 findings from 1 review
RR 1.26 [0.67, 2.38]
6 studies
GRADE not reported
RR 1.27 [0.44, 3.67]
5 studies
GRADE not reported
RR 1.03 [0.85, 1.25]
11 studies
GRADE not reported
Show 1 more finding
RR 0.87 [0.60, 1.27]
6 studies
GRADE not reported
Incidence of microleakage · Er,Cr:YSGG laser-prepared cavities restored with etch-and-rinse adhesive systems (in vitro)
Prior acid etching with etch-and-rinse adhesives did not significantly change microleakage after Er,Cr:YSGG preparation (RR 1.18, 95% CI 0.63-2.22; ungraded).
1 finding from 1 review
RR 1.18 [0.63, 2.22]
2 studies
GRADE not reported
Patient satisfaction (measured by patient satisfaction or aesthetic scales) · Patients with post-orthodontic white spot lesions and permanent dentition
In the single RCT, all bleached patients were satisfied with the aesthetic outcome, though the trial was at high risk of bias (ungraded).
1 finding from 1 review
Colour disparity between carious and non-affected enamel · Permanent teeth with post-orthodontic or artificial white spot lesions
Bleaching may diminish colour disparities between carious and non-affected areas (very low certainty).
1 finding from 1 review
no estimate extracted
3 studies
GRADE not reported
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found higher pulpotomy success with triple antibiotic paste than abscess remedy (100% vs 80%; statistically significant, P<0.05; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 TAP and 20 AR teeth): TAP 100% (20/20) vs abscess remedy 80% (16/20) clinical and radiographic success; difference statistically significant at 3, 6, 9, 12, 18 and 24 months (P<0.05);…
1 study · 40 participants
GRADE not reported
Plaque · Medically healthy individuals (adults and children, 6-60 years)
Placebo rinse did not significantly change plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Lower incisor inclination (lingual tipping and retrusion) · Children (approximately 11 years or older) with compromised mandibular first permanent molars
Bilateral lower first permanent molar extraction was associated with lingual tipping and retrusion of the lower incisors in one case-control study; ungraded.
1 finding from 1 review
Spontaneous space closure · Children aged 5 to 15 years undergoing first permanent molar extraction
Spontaneous post-extraction space closure did not differ significantly between the maxilla and mandible (pooled OR 2.06, 95% CI 0.46 to 9.28; 3 studies; I2 = 72%); ungraded.
1 finding from 1 review
Skeletal development (occlusal plane rotation, facial height) · Children (approximately 11 years or older) with compromised mandibular first permanent molars
Bilateral lower first permanent molar extraction was associated with counter-clockwise rotation of the occlusal plane and a mild decrease in lower anterior face height in one case-control study; ungraded.
1 finding from 1 review
Normando and Cavacami: decreased GnSN angle (P = 0.05), counter-clockwise rotation of the occlusal plane (mean 5.6 vs 12.6 degrees, P = 0.0001), and decreased lower anterior face height (P = 0.048). Table 3: Category…
1 study
GRADE not reported
Development and eruption of the second permanent molar · Children aged 5 to 15 years with a compromised first permanent molar
Root closure and eruption of the second permanent molar appeared accelerated on the extraction side in a single case-control study; ungraded and not statistically tested.
1 finding from 1 review
Development and eruption of the third molar · Children aged 5 to 15 years with a compromised first permanent molar
Development and eruption of the third molar appeared accelerated after early first permanent molar extraction in two studies (e.g., eruption OR 2.86, 95% CI 1.37 to 5.96); ungraded.
1 finding from 1 review
OR 2.86 [1.37, 5.96]
2 studies
GRADE not reported
Caries and/or fillings in adjacent teeth · Children aged 5 to 15 years with a compromised first permanent molar
One study found fewer decayed or filled proximal surfaces but more decayed or filled occlusal surfaces in arches with an extracted first permanent molar; ungraded.
1 finding from 1 review