Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Acellular dermal matrix patch led to lower presence of dry socket compared with no treatment; GRADE not reported.
1 finding from 1 review
Oral health indices · Residents of nursing homes and other long-term care facilities
Professional oral care led to higher oral health indices compared with usual oral care; GRADE not reported.
1 finding from 1 review
Sinus or fistula formation at last · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes sinus tract or fistula formation compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Choking · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries
No systematic reviews or studies assessed choking risk for RCF or NRCF (only BLW/BLISS); this is an evidence gap.
1 finding from 1 review
Change in systemic antibiotic use · Residents of nursing homes and other long-term care facilities
The review found no eligible studies for this question.
1 finding from 1 review
Choking · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries
No significant difference in choking risk was found between BLW/BLISS-fed and traditionally fed infants (ungraded).
1 finding from 1 review
Healing of MRONJ (mucosal integrity) · People with MRONJ referred for surgical treatment
It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).
1 finding from 1 review
Diabetic complications · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
The review found no eligible studies for this question.
1 finding from 1 review
Pain at 48 hours (VAS 0-10) · Adults (>18 years) with established dry socket following permanent tooth extraction
Topical anaesthetic gel (prilocaine-lidocaine) showed no clear difference in pain at 48 hours (VAS 0-10) compared with eugenol; GRADE not reported.
1 finding from 1 review
Postoperative pain intensity in the immediate postobturation period (up to 72 hours), continuous (VAS) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in postoperative pain intensity in the immediate postobturation period… compared with multiple-visit root canal treatment (two or more visits) (low certainty).
1 finding from 1 review
Healing of MRONJ (remission) · People with established (manifest) MRONJ
It is very uncertain whether teriparatide 56.5 microg weekly in addition to standard care changes healing of MRONJ (remission) compared with teriparatide 20 microg daily in addition to standard care (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Tap water irrigation (monoject syringe) led to lower presence of dry socket compared with no rinsing; GRADE not reported.
1 finding from 1 review
Number of caries in permanent teeth (DT index) · School children, primary school in Saudi Arabia
It is very uncertain whether referral to a specific dental treatment facility changes number of caries in permanent teeth (DT index) compared with generic advice letter to see a dentist (very low certainty).
1 finding from 1 review
Pain at 1 month · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
1 finding from 1 review
One study (Dhyani 2022) reported pain at 1 month: 60 teeth (all vital at enrolment, mechanical NiTi), 0 events (no participant reported pain at 1 month); no meta-analysis
1 study · 60 participants
GRADE not reported
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Honey (Manuka, topical) showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.2%); GRADE not reported.
1 finding from 1 review
Overweight/obesity risk · Healthy children aged 6–24 months in Western industrialized countries
BLISS did not show a statistically significant reduction in overweight/obesity risk at 24 months (low certainty).
1 finding from 1 review
Dental attendance · primary or secondary school pupils
Criteria-based screening (dentist refers using pre-established… showed no clear difference in dental attendance compared with no screening (low certainty).
1 finding from 1 review
CRP (mg/dL) at end of study · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with artemisia desertorum spreng (Yunnan); GRADE not reported.
1 finding from 1 review
MRONJ (incidence proportion) · People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ)
It is very uncertain whether dental extraction protocol with plasma rich in growth factors (PRGF)… changes MRONJ (incidence proportion) compared with standard dental extraction protocol without PRGF (very low certainty).
1 finding from 1 review