Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Fixed tooth-borne expansion (Hyrax) vs Fixed tooth-tissue-borne expansion (Haas)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne expansion (Hyrax) showed no clear difference in crossbite correction compared with fixed tooth-tissue-borne expansion (Haas) (moderate certainty).

1 finding from 1 review

Two-band palatal expander with slow expansion vs Two-band palatal expander with rapid expansion

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
  • Orthodontic treatment for posterior crossbites 2021 · Cochrane All outcomes
    7 months after start of treatment
    Martina 2012: slow 6.3 mm (SD 2.1) vs rapid 5.7 mm (SD 1.6); reported as no statistically significant difference in text (PUB2 MD 0.60, 95% CI -0.85 to 2.05); Table 1 lists P<0.001 (discrepant)
    1 study · 26 participants
    GRADE not reported

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

Reported improvement in the position of the ectopic canine measured from radiographs · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

Lower lip bumper vs No active treatment (control)

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether lower lip bumper changes amount of crowding (change in mandibular incisor crowding) at 6 months compared with no active treatment (control) (very low certainty).

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Amount of crowding (lower incisor crowding) at 10 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether cervical pull headgear changes amount of crowding (lower incisor crowding) at 2 years compared with minor interceptive procedures (control) (very low certainty).

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Endothelial function (flow-mediated dilation) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to higher endothelial function (flow-mediated dilation) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Induction chemotherapy plus locoregional treatment (radiotherapy and/or surgery) vs Locoregional treatment (radiotherapy and/or surgery) alone

Overall survival, induction platinum + 5-fluorouracil prior to surgery vs surgery alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).

1 finding from 1 review

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

Root resorption of adjacent permanent teeth caused by the PDC · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

Extraction of the primary (baby) canine (single primary tooth… showed no clear difference in root resorption of adjacent permanent teeth caused by the PDC compared with no extraction (non-intervention control); GRADE not reported.

1 finding from 1 review

Selective carious tissue removal (selective excavation, SE) vs Hall Technique (sealing with a preformed metal crown)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

It is very uncertain whether selective carious tissue removal (selective excavation, SE) changes failure of therapy compared with hall Technique (sealing with a preformed metal crown) (very low certainty).

2 findings from 1 review

Fixed tooth-borne expansion (quad-helix) vs observation

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne expansion (quad-helix) leads to higher crossbite correction compared with observation (no treatment) (high certainty).

1 finding from 1 review

Fixed tooth-borne expansion (quad-helix) vs observation

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne expansion (quad-helix) may leads to higher canine expansion (inter-canine distance) compared with observation (no treatment) (low certainty).

1 finding from 1 review

Chemotherapy regimen A (+/- locoregional treatment) vs Chemotherapy regimen B (+/- locoregional treatment)

Overall survival (total mortality), chemotherapy regimen A vs regimen B · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
1 finding from 1 review

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

Effect of severity of PDC displacement towards the midline on the proportion of successful eruptions · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
1 finding from 1 review

Vibrational appliance with fixed appliances vs Fixed appliances

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether vibrational appliance with fixed appliances changes amount of crowding (change in mandibular crowding) at 10 to 30 weeks compared with fixed appliances only / no vibrational appliance (control) (very low certainty).

1 finding from 1 review

ARP with allograft (bone graft) vs ARP with xenograft

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with allograft changes changes in vertical height of alveolar ridge (mm) compared with ARP with xenograft (very low certainty).

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in change in systolic blood pressure (SBP, mmHg) compared with no treatment (no periodontal treatment) (low certainty).

4 findings from 1 review
Show 1 more finding
  • Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
    Short term (follow-up 3 months) · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
    MD 0.59 [-9.18, 10.36]
    1 study · 55 participants
    Very low

Bone-borne expansion vs Fixed tooth-borne expansion (Hyrax)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Bone-borne expansion showed no clear difference in crossbite correction compared with fixed tooth-borne expansion (Hyrax) (low certainty).

1 finding from 1 review

Chemotherapy vs Placebo

Outcome not reported · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

The review found no eligible studies for this question.

1 finding from 1 review

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Incidence of successfully erupted PDC that were favourably positioned · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

Double primary (canine and first molar) tooth extraction showed no clear difference in incidence of successfully erupted PDC that were favourably positioned compared with single primary (canine) tooth extraction; GRADE not reported.

3 findings from 1 review