Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in brief Pain Inventory (BPI) - pain intensity, change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Prevalence of eruption/non-eruption of the palatally displaced permanent canine (successful eruption) · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Narrative (not pooled, not GRADE-rated). Leonardi 2004: successful eruption 80% with extraction plus cervical pull headgear, significantly higher than the untreated control group (Chi2 14.9; P<0.01). Baccetti 2008: the…
2 studies · 81 participants
GRADE not reported
Incidence or prevalence of root resorption of the impacted canine and/or incisors and cyst formation · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
The review found no eligible studies for this question.
1 finding from 1 review
Improvement in the vertical position or angulation of the ectopic canine, measured from radiographs · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Changes in the position of the displaced canine measured from radiographs, reported by both trials as medians (non-normal distribution): changes in the inclination of the canine to the midline, the distance of the…
2 studies
GRADE not reported
Pain on palpation of the affected/contralateral TMJ and masticatory muscles · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower pain on palpation of the affected/contralateral TMJ and masticatory… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Pain on palpation of the affected and contralateral TMJ and masticatory muscles presented similar frequencies regardless of the time (Analyses 1.4-1.12); no statistically significant differences reported. Point…
1 study · 40 participants
GRADE not reported
Extent of mandibular movement (maximum jaw opening, lateral and contralateral movement, jaw protrusion) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate showed no clear difference in extent of mandibular movement (maximum jaw opening, lateral and… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
None of the mean differences between interventions for the measures of jaw movements (maximum jaw opening, lateral movement to affected side, contralateral movement, jaw protrusion; Analyses 1.16-1.27) showed…
1 study · 40 participants
GRADE not reported
Pain-free maximum jaw opening (mm), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in pain-free maximum jaw opening (mm), change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Prevalence of eruption/non-eruption of the palatally displaced permanent canine (successful eruption) · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Narrative (not pooled, not GRADE-rated). Leonardi 2004: extraction plus headgear (80%) gave significantly higher eruption than extraction alone (50%) (Chi2 4.69; P<0.05). Baccetti 2008: extraction plus headgear was…
2 studies · 79 participants
GRADE not reported
Arthrocentesis
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Iontophoretically applied corticosteroids
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Reported pain (mm on VAS) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower reported pain (mm on VAS) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Brief Pain Inventory (BPI) - pain interference, change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in brief Pain Inventory (BPI) - pain interference, change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Physiotherapy modalities (physiotherapy, short-wave diathermy, ultrasound)
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Morphological changes of the TMJs (assessed by CT) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
1 finding from 1 review
Pain (on movement and on palpation of the affected TMJ) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
1 finding from 1 review
Data for pain on movement or pain on palpation of the affected TMJ (both at 1 week and 3 months) could not be extracted, as they are described as percentages of an unclear total number. Narratively, diclofenac sodium…
1 study
GRADE not reported
Open TMJ surgery (arthroplasty / total joint replacement)
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Change in the sagittal position of the upper first molars · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Prevalence of eruption/non-eruption of the palatally displaced permanent canine (successful eruption) · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Narrative summary (data not poolable, not GRADE-rated). Leonardi 2004: successful eruption of the permanent canine 50% in the extraction-only group, which was not significantly greater than the success rate in…
2 studies · 70 participants
GRADE not reported
Pain during function (proportion without significant improvement) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) led to lower pain during function (proportion without significant improvement) compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Six participants in the glucosamine group did not experience significant improvement in TMJ pain compared with seven in the ibuprofen group (Analysis 3.1); Fisher's exact test P = 0.73 (not significant, per the authors).
1 study · 45 participants
GRADE not reported
Clinical assessment: alveolar ridge healing (0 to 3 grading scale) · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)
Artificial bone graft: InFuse (collagen matrix) impregnated with… led to higher clinical assessment: alveolar ridge healing (0 to 3 grading scale) compared with traditional iliac crest cancellous bone graft; GRADE not reported.
1 finding from 1 review