Change in pain index · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral propranolol (beta-blocker) showed no clear difference in change in pain index compared with placebo; GRADE not reported.
1 finding from 1 review
Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Non-resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (vertical - VDH) compared with resorbable barrier + autogenous bone; GRADE not reported.
1 finding from 1 review
All treatments resulted in statistically significant bone gain, however no statistically significant differences were found between the three procedures (Chen 2005a). Vertical height of the defect (VDH).
1 study · 25 participants
GRADE not reported
Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
Fluconazole (absorbed from GI tract) showed no clear difference in mycological: eradication of oral candidiasis compared with ketoconazole (absorbed from GI tract); GRADE not reported.
1 finding from 1 review
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Low dose rate interstitial radiotherapy showed no clear difference in locoregional control compared with high dose rate interstitial radiotherapy; GRADE not reported.
1 finding from 1 review
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Hyperfractionated/accelerated split course vs accelerated boost (Fu 1995, feasibility study, 75 participants): authors report no significant difference in total mortality; data not presented in a way that allows…
1 study · 75 participants
GRADE not reported
Calculus · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review
Clinical: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
Miconazole 50 mg tablet (partially absorbed) showed no clear difference in clinical: eradication of oral candidiasis compared with miconazole 500 mg gel (partially absorbed); GRADE not reported.
1 finding from 1 review
Participants' assessment of improvement of pain in right TMJ (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral clonazepam (benzodiazepine) showed no clear difference in participants' assessment of improvement of pain in right TMJ (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
No improvement in TMJ pain on external palpation · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral prazepam (benzodiazepine) showed no clear difference in no improvement in TMJ pain on external palpation compared with placebo; GRADE not reported.
2 findings from 1 review
Anxiety control and overall response to treatment during tooth extraction · Children aged 10 to 16 years undergoing orthodontic extractions (Braithwaite 2005)
1 finding from 1 review
Hypnosis did not provide sufficient anxiety control during tooth extraction, and overall response to treatment remained statistically lower than response to inhalation sedation with nitrous oxide and oxygen (i.e. the…
1 study · 10 participants
GRADE not reported
Clinical: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
Fluconazole (absorbed from GI tract) showed no clear difference in clinical: eradication of oral candidiasis compared with itraconazole (absorbed from GI tract); GRADE not reported.
1 finding from 1 review
Change in probing pocket depth (PPD) · Adults with dental implants and peri-implant mucositis at baseline
Mechanical debridement with titanium curettes showed no clear difference in change in probing pocket depth compared with mechanical debridement with ultrasonic device; GRADE not reported.
1 finding from 1 review
Pain on palpation of right masseter muscle (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral clonazepam (benzodiazepine) showed no clear difference in pain on palpation of right masseter muscle (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Non-resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (horizontal - HDD) compared with resorbable barrier + autogenous bone; GRADE not reported.
1 finding from 1 review
All treatments resulted in statistically significant bone gain, however no statistically significant differences were found between the three procedures (Chen 2005a). Horizontal depth of the defect (HDD).
1 study · 25 participants
GRADE not reported
Prosthesis failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower prosthesis failure compared with no augmentation; GRADE not reported.
1 finding from 1 review
In total two implants were lost in the autogenous bone group, whereas no complications or failures occurred in the non-augmented control group; underpowered, no statistically significant difference (Chen 2005b).
1 study · 26 participants
GRADE not reported
Disease-free survival · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Altered fractionation radiotherapy (hyperfractionated and/or… showed no clear difference in disease free survival compared with conventional (standard) fractionation radiotherapy; GRADE not reported.
2 findings from 1 review
No improvement in spontaneous TMJ pain · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral prazepam (benzodiazepine) showed no clear difference in no improvement in spontaneous TMJ pain compared with placebo; GRADE not reported.
2 findings from 1 review
Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Diclofenac showed no clear difference in average pain scores (0-100 VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Severity of injury by self report · Adults (16 years of age and older) who present to any healthcare setting with dental or facial injury
The review found no eligible studies for this question.
1 finding from 1 review
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Human placental extract led to higher improvement in mucositis compared with disprin (aspirin/betamethasone); GRADE not reported.
1 finding from 1 review