Gap finder
Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
71 questions in 6 reviews · cluster CL0264
current versionsNo studies 23 · 32.4%Ungraded 28 · 39.4%Very low 16 · 22.5%Low 1 · 1.4%Moderate 3 · 4.2%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
38% SDF (one-time application) vs Inactive control (water or no treatment) New coronal carious lesions or fillings on permanent (first) molars (caries prevention) · Children with dental caries in permanent (first) molars · 18 months, Monse 2012 (SDF one-time, no toothbrushing programme; Philippines) A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Mean new caries increment (surfaces) 0.12 | 1 study · 1016 participants | Ungraded |
38% SDF one-time application vs Information unavailable new carious lesions or fillings · children with caries in permanent first molars · 12 months A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Preventative fraction (%) 57 | 1 study · 141 participants | Ungraded |
38% SDF plus oral health education vs oral health instruction plus water new root-surface carious lesions or restorations · community-dwelling older adults with root caries · 24 months A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Preventative fraction (%) 33 | 1 study · 266 participants | Ungraded |
38% SDF varnish plus oral health instruction vs oral health instruction plus water new root-surface carious lesions or restorations · older adults with root caries · 36 months A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Preventative fraction (%) 71 | 1 study · 306 participants | Ungraded |
38% SDF every 12 months vs water every 12 months new carious lesions or fillings at fissure-site level · children with caries in permanent molars · 24 months A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Preventative fraction (%) 52 | 1 study · 501 participants | Ungraded |
Silver diamine fluoride (SDF) vs Any (current minimally invasive techniques) Not applicable (no eligible studies) · Adults with coronal (crown) dental caries in permanent teeth A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | The review states there was a lack of studies on the effects of SDF on coronal caries in adults; included adult studies addressed only root caries. | 0 studies | No studies |
38% SDF one-time application without brushing programme vs no treatment without brushing programme new carious lesions or fillings · schoolchildren with caries in permanent first molars · 18 months A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Mean new caries increment (surfaces) 0.12 | 1 study · 1016 participants | Ungraded |
38% SDF (one-time application) vs Information unavailable New coronal carious lesions or fillings on permanent (first) molars (caries prevention) · Children with dental caries in permanent (first) molars · 12 months, Mauro 2004 (permanent first molars, one-time SDF; Argentina) A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Prevented Fraction 57 | 1 study · 141 participants | Ungraded |
OHI + 38% SDF (applied every 12 months) vs oral health instruction plus water new root-surface carious lesions or restorations · community-dwelling older adults with root caries · 24 months A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent… (2023) | Preventative fraction (%) 28 | 1 study · 266 participants | Ungraded |
Prior SDF application without a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Glass-ionomer cement bonded to caries-affected dentin (in vitro) · Immediate bond strength, Caries-affected dentin (without rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD 0.26 [-0.30, 0.82] | 4 studies · 130 participants | Ungraded |
Prior SDF application without a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Dental adhesives bonded to sound dentin (in vitro) · Immediate bond strength, Sound dentin (without rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD 17.52 [5.81, 29.22] | 3 studies · 136 participants | Ungraded |
Prior application of silver diamine fluoride (SDF), with or without a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Dental adhesives/resin composite bonded to dentin (in vitro), sound or caries-affected · Immediate bond strength, Overall (all dentin conditions and rinsing protocols) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD 7.12 [1.38, 12.85] | 11 studies · 526 participants | Ungraded |
Prior SDF application with a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Glass-ionomer cement bonded to sound dentin (in vitro) · Immediate bond strength, Sound dentin (with rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD -1.11 [-3.47, 1.25] | 4 studies · 57 participants | Ungraded |
Prior SDF application with a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Glass-ionomer cement bonded to caries-affected dentin (in vitro) · Immediate bond strength, Caries-affected dentin (with rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD -0.36 [-1.07, 0.35] | 5 studies · 178 participants | Ungraded |
Prior application of silver diamine fluoride (SDF), with or without a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Glass-ionomer cement bonded to dentin (in vitro), sound or caries-affected · Immediate bond strength, Overall (all dentin conditions and rinsing protocols) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD -0.11 [-0.54, 0.31] | 11 studies · 583 participants | Ungraded |
Prior SDF application without a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Glass-ionomer cement bonded to sound dentin (in vitro) · Immediate bond strength, Sound dentin (without rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD 0.26 [-0.20, 0.73] | 5 studies · 218 participants | Ungraded |
Prior SDF application with a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Dental adhesives bonded to sound dentin (in vitro) · Immediate bond strength, Sound dentin (with rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD 7.11 [-0.57, 14.79] | 7 studies · 318 participants | Ungraded |
Silver diamine fluoride (30% SDF) vs Atraumatic restorative treatment (ART) Patient discomfort during treatment (anxiety scale) · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · During/after the treatment procedure Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic… (2022) | Only one study assessed patient discomfort during treatment (SDF vs ART) using the patient's anxiety scale, obtaining almost overlapping results (p = 0.15). | 1 study · 67 participants | Ungraded |
Prior SDF application with a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Dental adhesives bonded to caries-affected dentin (in vitro) · Immediate bond strength, Caries-affected dentin (with rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | MD -4.79 [-9.19, -0.40] | 3 studies · 72 participants | Ungraded |
Prior SDF application without a rinsing step vs No prior SDF application (untreated dentin control) Immediate bond strength (MPa) · Dental adhesives bonded to caries-affected dentin (in vitro) · Immediate bond strength, Caries-affected dentin (without rinsing step) Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated… (2022) | no estimate extracted | 1 study | Ungraded |
10% silver diamine fluoride (SDF) vs Glass ionomer restoration and tooth-brushing Remineralisation of early enamel caries · Children with early enamel caries in erupting permanent first molars Caries remineralisation and arresting effect in children by professionally applied fluoride treatment - a… (2016) | A pilot study found 10% silver diamine fluoride therapy, glass ionomer restoration, and tooth-brushing had a similar effect in remineralising early enamel caries. | 1 study | Ungraded |