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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
371 questions in 6 reviews · cluster CL0008
current versionsNo studies 0 · 0%Ungraded 371 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
TT+TC genotypes vs CC genotype Dental caries · Children (<18 years) with vs without dental caries · Dominant model (TT+TC vs CC), Permanent dentition Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… (2024) | OR 0.72 [0.48, 1.07] | NR | Ungraded |
TT genotype vs TC+CC genotypes Dental caries · Children (<18 years) with vs without dental caries · Recessive model (TT vs TC+CC), Primary dentition Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… (2024) | OR 1.49 [0.97, 2.27] | NR | Ungraded |
CC+TT (homozygous) genotypes vs CT (heterozygous) genotype Dental caries · Children (<18 years) with vs without dental caries · Over-dominant model (CC+TT vs CT) Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… (2024) | OR 0.83 [0.67, 1.04] | 3 studies · 1329 participants | Ungraded |
A allele vs G allele Dental caries · Children (<18 years) with vs without dental caries · Allelic model (A vs G) Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… (2024) | OR 1.07 [0.70, 1.64] | 3 studies · 855 participants | Ungraded |
TT+CC (homozygous) genotypes vs TC (heterozygous) genotype Dental caries · Children (<18 years) with vs without dental caries · Over-dominant model (TT+CC vs TC), Caucasian ethnicity Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… (2024) | OR 1.26 [0.88, 1.80] | NR | Ungraded |
T allele vs C allele Dental caries · Children (<18 years) with vs without dental caries · Allelic model (T vs C), Caucasian ethnicity Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… (2024) | OR 1.00 [0.72, 1.39] | NR | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of TAS2R43 (chr12p13.2) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), TAS2R43 (chr12p13.2); 27 (3) tissues; significant (Bonferroni p < 3.09x10-6) Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) 1.80 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of SMIM10L1 (chr12p13.2) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), SMIM10L1 (chr12p13.2); 46 (3) tissues; significant (Bonferroni p < 3.09x10-6) Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) -0.35 | 5 studies · 2974 participants | Ungraded |
Common genetic variants genome-wide (GWAS; ~3.9 million SNPs with MAF > 5%) vs ECC-unaffected children (per-allele case-control association) Early childhood caries (ECC) - association at lead SNP rs8091366 (18:24715618; nearest gene(s) CHST9, KCTD1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs8091366 (18:24715618); effect/non-effect allele A/G; MAF 0.52; direction across 5 cohorts +++++ Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (Stouffer's combined Z, 5 cohorts) 4.476 | 5 studies · 2974 participants | Ungraded |
Common genetic variants genome-wide (GWAS; ~3.9 million SNPs with MAF > 5%) vs ECC-unaffected children (per-allele case-control association) Early childhood caries (ECC) - association at lead SNP rs563135 (10:115067899; nearest gene(s) TCF7L2, CASP7) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs563135 (10:115067899); effect/non-effect allele A/C; MAF 0.51; direction across 5 cohorts ----- Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (Stouffer's combined Z, 5 cohorts) -4.532 | 5 studies · 2974 participants | Ungraded |
Common genetic variants genome-wide (GWAS; ~3.9 million SNPs with MAF > 5%) vs ECC-unaffected children (per-allele case-control association) Early childhood caries (ECC) - association at lead SNP rs1044956 (7:24854765; nearest gene(s) OSBPL3, NPVF) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs1044956 (7:24854765); effect/non-effect allele A/G; MAF 0.49; direction across 5 cohorts +++++ Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (Stouffer's combined Z, 5 cohorts) 4.551 | 5 studies · 2974 participants | Ungraded |
Common genetic variants genome-wide (GWAS; ~3.9 million SNPs with MAF > 5%) vs ECC-unaffected children (per-allele case-control association) Early childhood caries (ECC) - association at lead SNP rs9889096 (16:13575143; nearest gene(s) SHISA9) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs9889096 (16:13575143); effect/non-effect allele T/G; MAF 0.50; direction across 5 cohorts --+-- Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (Stouffer's combined Z, 5 cohorts) -4.541 | 5 studies · 2974 participants | Ungraded |
Common genetic variants genome-wide (GWAS; ~3.9 million SNPs with MAF > 5%) vs ECC-unaffected children (per-allele case-control association) Early childhood caries (ECC) - association at lead SNP rs7325099 (13:28104496; nearest gene(s) LNX2, POLR1D, RPL21) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs7325099 (13:28104496); effect/non-effect allele A/C; MAF 0.50; direction across 5 cohorts ++?++ Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (Stouffer's combined Z, 5 cohorts) 4.485 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of LACC1 (chr13q14.11) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), LACC1 (chr13q14.11); 48 (4) tissues; suggestive (p < 1.0x10-4) ; flagged possible false positive Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) 0.10 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of NRAD1 (LINC00284) (chr13q14.11) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), NRAD1 (LINC00284) (chr13q14.11); 30 (5) tissues; significant (Bonferroni p < 3.09x10-6) ; flagged possible false positive Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) 0.13 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of TAS2R31 (chr12p13.2) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), TAS2R31 (chr12p13.2); 41 (4) tissues; suggestive (p < 1.0x10-4) Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) -0.25 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of TAS2R14 (chr12p13.2) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), TAS2R14 (chr12p13.2); 48 (4) tissues; significant (Bonferroni p < 3.09x10-6) Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) 0.47 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of IGSF5 (chr21q22.2) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), IGSF5 (chr21q22.2); 27 (11) tissues; suggestive (p < 1.0x10-4) ; flagged possible false positive Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) 0.63 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of LINC02905 (C8orf49) (chr8p23.1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), LINC02905 (C8orf49) (chr8p23.1); 9 (3) tissues; significant (Bonferroni p < 3.09x10-6) ; flagged possible false positive Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) -0.35 | 5 studies · 2974 participants | Ungraded |
Common genetic variants genome-wide (GWAS; ~3.9 million SNPs with MAF > 5%) vs ECC-unaffected children (per-allele case-control association) Early childhood caries (ECC) - association at lead SNP rs76823412 (8:134690570; nearest gene(s) ST3GAL1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs76823412 (8:134690570); effect/non-effect allele T/C; MAF 0.47; direction across 5 cohorts +++++ Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (Stouffer's combined Z, 5 cohorts) 4.806 | 5 studies · 2974 participants | Ungraded |
Common genetic variants genome-wide (GWAS; ~3.9 million SNPs with MAF > 5%) vs ECC-unaffected children (per-allele case-control association) Early childhood caries (ECC) - association at lead SNP rs74470773 (3:33958083; nearest gene(s) PDCD6IP) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs74470773 (3:33958083); effect/non-effect allele T/C; MAF 0.47; direction across 5 cohorts ----- Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (Stouffer's combined Z, 5 cohorts) -4.589 | 5 studies · 2974 participants | Ungraded |
Genetically predicted gene expression (TWAS; S-PrediXcan with GTEx v8 cis-eQTL across 49 tissues; cross-tissue S-MultiXcan) vs ECC-unaffected children (association of genetically predicted expression) Early childhood caries (ECC) - association with genetically predicted expression of CDH17 (chr8q22.1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), CDH17 (chr8q22.1); 23 (5) tissues; significant (Bonferroni p < 3.09x10-6) Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide… (2022) | Z-score (cross-tissue mean, S-MultiXcan) 1.74 | 5 studies · 2974 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT/CC genotype vs TT genotype (dominant model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Mixed dentition caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.37 [0.81, 2.33] | 2 studies · 270 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs TT genotype (homozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Asian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.38 [0.55, 3.50] | 5 studies · 1932 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs CT/TT genotype (recessive model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Mixed dentition caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.23 [0.66, 2.29] | 2 studies · 270 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs CT/TT genotype (recessive model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Deciduous tooth decay Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 0.80 [0.05, 12.89] | 2 studies · 929 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs CT/TT genotype (recessive model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Overall Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.38 [1.03, 1.84] | 7 studies · 2470 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs C allele vs T allele (allele contrast model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Caucasian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.16 [0.90, 1.50] | 2 studies · 538 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT/CC genotype vs TT genotype (dominant model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Permanent tooth caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.78 [0.41, 7.73] | 3 studies · 1271 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs CT/TT genotype (recessive model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Caucasian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.33 [0.91, 1.95] | 2 studies · 538 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs C allele vs T allele (allele contrast model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Permanent tooth caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.40 [1.11, 1.77] | 3 studies · 1271 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs TT genotype (homozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Overall Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 0.83 [0.29, 2.40] | 7 studies · 2470 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs C allele vs T allele (allele contrast model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Overall Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.24 [1.07, 1.44] | 7 studies · 2470 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT genotype vs TT genotype (heterozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Caucasian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 0.93 [0.56, 1.56] | 2 studies · 538 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT/CC genotype vs TT genotype (dominant model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Asian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.67 [0.97, 2.87] | 5 studies · 1932 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT genotype vs TT genotype (heterozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Deciduous tooth decay Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.40 [0.91, 2.15] | 2 studies · 929 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs TT genotype (homozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Deciduous tooth decay Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.28 [0.08, 21.28] | 2 studies · 929 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs TT genotype (homozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Mixed dentition caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.44 [0.72, 2.85] | 2 studies · 270 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT genotype vs TT genotype (heterozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Permanent tooth caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.65 [0.33, 8.35] | 3 studies · 1271 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT/CC genotype vs TT genotype (dominant model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Caucasian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.05 [0.65, 1.71] | 2 studies · 538 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT/CC genotype vs TT genotype (dominant model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Deciduous tooth decay Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.39 [0.91, 2.15] | 2 studies · 929 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs TT genotype (homozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Permanent tooth caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 0.29 [0.16, 0.53] | 3 studies · 1271 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs TT genotype (homozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Caucasian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 0.62 [0.13, 3.09] | 2 studies · 538 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs C allele vs T allele (allele contrast model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Deciduous tooth decay Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.10 [0.87, 1.38] | 2 studies · 929 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs C allele vs T allele (allele contrast model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Mixed dentition caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.26 [0.87, 1.82] | 2 studies · 270 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs CT/TT genotype (recessive model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Permanent tooth caries Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.44 [1.03, 2.00] | 3 studies · 1271 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT genotype vs TT genotype (heterozygous model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Asian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.67 [0.96, 2.90] | 5 studies · 1932 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs C allele vs T allele (allele contrast model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Asian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.28 [1.06, 1.54] | 5 studies · 1932 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CT/CC genotype vs TT genotype (dominant model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Overall Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.45 [0.96, 2.19] | 7 studies · 2470 participants | Ungraded |
TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs CT/TT genotype (recessive model) Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Asian Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. (2021) | OR 1.45 [0.93, 2.26] | 5 studies · 1932 participants | Ungraded |