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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
19 questions in 3 reviews · intervention: Nutritional supplement · outcome domain: Caries (unspecified)
current versionsNo studies 0 · 0%Ungraded 19 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Prenatal vitamin D level ≤50 nmol/L vs Normal or sufficient prenatal vitamin D level Dental caries · Children aged 2 to 8 years · Maternal pregnancy to child age 2 to 8 years, Vitamin D threshold ≤50 nmol/L Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.30 [1.17, 1.43] | 4 studies | Ungraded |
Prenatal vitamin D deficiency (maternal 25(OH)D measured at gestational weeks 6 to 38) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy · Maternal 25(OH)D measured at gestational weeks 6 to 38, Gestational-age subgroup: weeks 6 to 38 Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.32 [1.04, 1.59] | 4 studies | Ungraded |
Prenatal vitamin D deficiency measured at 6 to 38 gestational weeks vs Normal or sufficient prenatal vitamin D level Dental caries · Children aged 2 to 8 years · Maternal gestational weeks 6 to 38, Vitamin D measurement at 6 to 38 gestational weeks Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.32 | NR | Ungraded |
Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) Dental caries in children · Children aged 6 to 8 years whose mothers' prenatal vitamin D status was assessed · Prenatal exposure; dental caries at 6 to 8 years, Children's age subgroup: 6 to 8 years Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.07 [0.84, 1.30] | 1 study | Ungraded |
Prenatal vitamin D deficiency (maternal 25(OH)D measured at gestational weeks 24 to 38) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy · Maternal 25(OH)D measured at gestational weeks 24 to 38, Gestational-age subgroup: weeks 24 to 38 Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.30 [1.15, 1.45] | 4 studies | Ungraded |
Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy · Prenatal exposure; dental caries assessed in children aged 2 to 8 years, Overall (all studies pooled) Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.35 [1.22, 1.47] | 12 studies · 11021 participants | Ungraded |
Prenatal vitamin D deficiency (PVDD) vs Normal or sufficient prenatal vitamin D level Dental caries · Children aged 2 to 8 years · Maternal pregnancy to child age 2 to 8 years, Meta-regression adjusted for gestational age, child age, and maternal vitamin D level Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.28 [1.23, 1.33] | NR | Ungraded |
Prenatal vitamin D level ≤35 nmol/L vs Normal or sufficient prenatal vitamin D level Dental caries · Children aged 2 to 8 years · Maternal pregnancy to child age 2 to 8 years, Vitamin D threshold ≤35 nmol/L Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.36 [1.20, 1.53] | 9 studies | Ungraded |
Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy · Prenatal exposure; dental caries in children aged 2 to 8 years, Publication-bias adjustment: Trim & Fill corrected pooled estimate Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.28 [1.14, 1.48] | NR | Ungraded |
Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) Dental caries in children · Children aged 4 to 6 years whose mothers' prenatal vitamin D status was assessed · Prenatal exposure; dental caries at 4 to 6 years, Children's age subgroup: 4 to 6 years Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) | OR 1.44 [1.32, 1.56] | 8 studies | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children (<19 years) Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.22 [1.18, 1.25] | 13 studies · 19205 participants | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children with permanent dentition (>12 years) · Permanent dentition Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.28 [1.21, 1.35] | 2 studies | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children with deciduous dentition (<6 years) · Deciduous dentition Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.68 [1.57, 1.79] | 6 studies | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children (<19 years) · Cross-sectional studies Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.19 [1.14, 1.24] | 5 studies | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children (<19 years) · Cohort studies Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.62 [1.51, 1.74] | 5 studies | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children with mixed dentition (6 to 12 years) · Mixed dentition Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.08 [1.04, 1.12] | 4 studies | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children (<19 years) · Adjusted for confounders Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.16 [1.10, 1.22] | NR | Ungraded |
Vitamin D deficiency (serum 25(OH)D < 50 nmol/L) vs Normal vitamin D level (serum 25(OH)D ≥ 50 nmol/L) Dental caries · Children (<19 years) · Case-control studies Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review… (2023) | RR 1.05 [1.00, 1.09] | 3 studies | Ungraded |
Vitamin D supplementation vs Placebo or control Dental caries · Children Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | RR 0.53 [0.43, 0.65] | 38 studies · 1513 participants | Ungraded |