Findings

What do systematic reviews say?

1,923 questions · 1,956 findings · 143 reviews · Musculoskeletal

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No studies found 555 · 28.4%GRADE not reported 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Intervention not reported

Self‐reported pain VAS. Scale from: 0 to 10. · patients with patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Low

Intervention not reported

Disease activity DAS · patients with patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 281 participants
High

Intervention not reported

Radiological damage Joint score radiographics · patients with patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 305 participants
High

Intervention not reported

Small patient number · patients with patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 participants
GRADE not reported

Intervention not reported

Self‐reported pain VAS. Scale from: 0 to 10. · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Moderate

Intervention not reported

Disease activity · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 74 participants
Moderate

Intervention not reported

Radiological damage ‐ not measured · patients with Rheumatoid Arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Small patient number · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 participants
GRADE not reported

Intervention not reported

Functional ability AIMS . Scale from: 0 to 10. · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Low

Intervention not reported

Muscle strength Isometric extension · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Low

Intervention not reported

Self‐reported pain AIMS. Scale from: 0 to 10. · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Moderate

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

ACR 50% improvement · patients with rheumatoid arthritis

Abatacept (2 and 10mg/kg) + DMARDs/biologic probably leads to higher ACR 50% improvement compared with placebo + DMARDs/biologic (moderate certainty).

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
RR 2.21 [1.73, 2.82]
3 studies · 993 participants
Moderate

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Pain Visual analog scale Scale from 0 to 100 (lower is better) · patients with rheumatoid arthritis

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1425 participants
Moderate

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Physical function · patients with rheumatoid arthritis

Abatacept (2 and 10mg/kg) + DMARDs/biologic probably leads to higher improvement in physical function (HAQ: greater than 0.3 increase… compared with placebo + DMARDs/biologic (moderate certainty).

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
RR 1.62 [1.35, 1.95]
1 study · 638 participants
Moderate

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Achievement of low disease activity state (DAS 28 less than 3.2, scale 0‐10) · patients with rheumatoid arthritis

Abatacept (2 and 10mg/kg) + DMARDs/biologic probably leads to higher achievement of low disease activity state (DAS 28 less than 3.2,… compared with placebo + DMARDs/biologic (moderate certainty).

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
RR 4.33 [2.84, 6.59]
1 study · 638 participants
Moderate

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Total serious adverse events · patients with rheumatoid arthritis

Abatacept (2 and 10mg/kg) + DMARDs/biologic showed no clear difference in total serious adverse events compared with placebo + DMARDs/biologic (moderate certainty).

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
RR 1.05 [0.87, 1.28]
6 studies · 3151 participants
Moderate

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Radiographic progression · patients with rheumatoid arthritis

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 586 participants
Moderate

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Long‐term serious adverse events · patients with rheumatoid arthritis

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 950 participants
Low

Intervention not reported

Pain Various validated pain scales · Patients with osteoarthritis of the knee or hip

The intervention showed no clear difference in pain Various validated pain scales (moderate certainty).

1 finding from 1 review

S‐Adenosylmethionine for osteoarthritis of the knee or hip 2009 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 533 participants
Moderate

Intervention not reported

Function Various validated function scales · Patients with osteoarthritis of the knee or hip

The intervention showed no clear difference in function Various validated function scales (low certainty).

1 finding from 1 review

S‐Adenosylmethionine for osteoarthritis of the knee or hip 2009 · Cochrane Headline outcomes only
SMD 0.02
3 studies · 542 participants
Low