Findings

What do systematic reviews say?

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

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No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

IUI in a natural cycle vs TI

Live birth rate · couples with male subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IUI in a stimulated cycle vs TI

OHSS · couples with male subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IUI in a stimulated cycle vs TI

Pregnancy rate per couple (all cycles) · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes pregnancy rate per couple (all cycles) compared with TI (very low certainty).

2 findings from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 3.14 [0.12, 81.35]
Studies not reported
Very low
Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.51 [0.74, 3.07]
Studies not reported
Very low

IUI in a stimulated cycle vs IUI

Live birth rate per couple · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes live birth rate per couple (all cycles) compared with IUI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.34 [0.77, 2.33]
Studies not reported
Very low

IUI in a stimulated cycle vs IUI

OHSS · couples with male subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IUI in a stimulated cycle vs IUI

Pregnancy rate per couple (all cycles) · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes pregnancy rate per couple (all cycles) compared with IUI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.68 [1, 2.82]
Studies not reported
Very low

IUI in a stimulated cycle vs IUI

Miscarriage · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes miscarriage rate per couple compared with IUI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.06 [0.2, 5.63]
Studies not reported
Very low

IVF vs IUI

Live birth rate per couple · couples with male subfertility

IVF showed no clear difference in live birth rate per couple (all cycles) compared with IUI (low certainty).

2 findings from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 0.77 [0.25, 2.35]
Studies not reported
Low
Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.03 [0.43, 2.45]
Studies not reported
Very low

IVF vs IUI

OHSS · couples with male subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVF vs IUI

OHSS per couple · couples with male subfertility

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

IUI in a natural cycle vs TI

OHSS · couples with male subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVF vs IUI

Pregnancy rate per couple (all cycles) · couples with male subfertility

It is very uncertain whether IVF changes pregnancy rate per couple (all cycles) compared with IUI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.27 [0.33, 4.97]
Studies not reported
Very low

IUI in a natural cycle vs TI

Pregnancy rate per couple (all cycles) · couples with male subfertility

It is very uncertain whether IUI in natural cycles changes pregnancy rate per couple (all cycles) compared with TI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 4.57 [0.21, 101.61]
Studies not reported
Very low

IUI in a stimulated cycle vs TI

Live birth rate per couple · couples with male subfertility

IUI in stimulated cycles showed no clear difference in live birth rate per couple (all cycles) compared with TI (low certainty).

2 findings from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 0.89 [0.3, 2.59]
Studies not reported
Low
Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 3.14 [0.12, 81.35]
Studies not reported
Very low

IUI in a stimulated cycle vs TI

OHSS per couple · couples with male subfertility

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

IUI in a stimulated cycle vs TI

Multiple pregnancy rate · couples with male subfertility

IUI in stimulated cycles showed no clear difference in multiple pregnancy rate per couple compared with TI (low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 3.15 [0.12, 79.69]
Studies not reported
Low

IUI in a stimulated cycle vs TI

Miscarriage · couples with male subfertility

IUI in stimulated cycles showed no clear difference in miscarriage rate per couple compared with TI (low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.03 [0.19, 5.42]
Studies not reported
Low

Human albumin vs placebo or no treatment

Moderate or severe OHSS · women at high risk of OHSS

It is very uncertain whether human albumin changes moderate or severe OHSS compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Volume expanders for the prevention of ovarian hyperstimulation syndrome 2016 · Cochrane Headline outcomes only
OR 0.67 [0.47, 0.95]
7 studies · 1452 participants
Very low

Mannitol vs placebo / no treatment

Live birth · women at high risk of OHSS

The review found no eligible studies for this question.

1 finding from 1 review

Volume expanders for the prevention of ovarian hyperstimulation syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mannitol vs placebo / no treatment

Pregnancy rate · women at high risk of OHSS

Mannitol showed no clear difference in pregnancy rate compared with placebo / no treatment (low certainty).

1 finding from 1 review

Volume expanders for the prevention of ovarian hyperstimulation syndrome 2016 · Cochrane Headline outcomes only
OR 0.85 [0.47, 1.55]
1 study · 226 participants
Low