Quality of life: number of participants with clinically significant improvement (≥ 4 units) in SGRQ total score · patients with stable chronic obstructive pulmonary disease
Aclidinium bromide leads to higher quality of life Number of patients who achieved at least 4 units… compared with placebo (high certainty).
1 finding from 1 review
Six‐minute walk distance · patients with stable chronic obstructive pulmonary disease
1 finding from 1 review
Hospital admission (exacerbation) · patients with stable chronic obstructive pulmonary disease
Aclidinium bromide leads to lower hospital admissions due to exacerbations compared with placebo (high certainty).
1 finding from 1 review
Non‐fatal serious adverse events · patients with stable chronic obstructive pulmonary disease
Aclidinium bromide showed no clear difference in non‐fatal serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
Mortality (all‐cause) · patients with stable chronic obstructive pulmonary disease
1 finding from 1 review
Exacerbations requiring steroids, antibiotics or both · patients with stable chronic obstructive pulmonary disease
It is very uncertain whether aclidinium bromide changes exacerbations requiring steroids, antibiotics or both compared with tiotropium (very low certainty).
1 finding from 1 review
Quality of life St George's Respiratory Questionnaire (SGRQ) score · patients with stable chronic obstructive pulmonary disease
1 finding from 1 review
Intervention not reported
Health‐related quality of life · participants with asthma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with asthma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Lung function (FEV1, PEF) · participants with asthma
1 finding from 1 review
Intervention not reported
Symptoms · participants with asthma
1 finding from 1 review
Intervention not reported
Adverse events · participants with asthma
1 finding from 1 review
Intervention not reported
Health‐related quality of life · participants with exercise‐induced asthma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with exercise‐induced asthma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Lung function (FEV1, PEF) · participants with exercise‐induced asthma
1 finding from 1 review
no estimate extracted
1 study · 8 participants
Low
Intervention not reported
Adverse events · participants with exercise‐induced asthma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Hospital admissions · adults with acute asthma
The intervention leads to lower hospital admissions (high certainty).
1 finding from 1 review
Intervention not reported
Intensive care unit (ICU) admissions · adults with acute asthma
The intervention showed no clear difference in intensive care unit (ICU) admissions (low certainty).
1 finding from 1 review
Intervention not reported
Length of hospital stay (days) · adults with acute asthma
1 finding from 1 review
Intervention not reported
ED treatment duration (minutes) · adults with acute asthma
1 finding from 1 review