Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,119 questions · 2,206 findings · 117 reviews · Common Mental Disorders

No studies found 387 · 17.5%GRADE not reported 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

Psychological therapy vs Waitlist/Usual Care

Secondary outcome: acceptability of treatment · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy probably leads to lower acceptability 1 ‐ proportion of participants withdrawing during… compared with usual care or waiting list (moderate certainty).

1 finding from 1 review

Psychological therapy vs Waitlist/Usual Care

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy may leads to higher treatment response at end of treatment CGI‐improvement/Global… compared with usual care or waiting list (low certainty).

1 finding from 1 review

Psychological therapy vs enhanced or structured care

Secondary outcome: acceptability of treatment · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy showed no clear difference in acceptability 1 ‐ proportion of participants withdrawing during… compared with enhanced or structured care (moderate certainty).

1 finding from 1 review

Intervention not reported

Achieved recovery according to predetermined criteria (no longer meeting criteria for depression on K‐SADS or meeting a priori criteria for response on a depression checklist, assessed between 4 and 10 weeks of onset of treatment) · children and adolescents with depression

The intervention showed no clear difference in achieved recovery according to predetermined criteria (no longer… (low certainty).

1 finding from 1 review

Intervention not reported

Change in depression checklist scores (BID, CDI, CDRS, DACL or HAM‐D from baseline to between 2 and 10 weeks) · children and adolescents with depression
1 finding from 1 review

Intervention not reported

Change in clinical global assessment scale scores (CGI scale or CGAS rated between 4 and 10 weeks of onset of treatment) · children and adolescents with depression
1 finding from 1 review

Intervention not reported

Number of withdrawals (occurring between 4 and 10 weeks of onset of treatment) · children and adolescents with depression

The intervention showed no clear difference in number of withdrawals (occurring between 4 and 10 weeks of onset of… (low certainty).

1 finding from 1 review

Sildenafil vs placebo

Endpoint International Index of Erectile Function (IIEF) total scores (The IIEF is a self‐report measure with 15 questions examining erectile function, orgasmic function, sexual desire, and intercourse satisfaction. Maximum possible score 75) · people with antidepressant‐induced sexual dysfunction
1 finding from 1 review