Volume‐targeted vs pressure‐limited ventilation: additional findings
- Volume‐targeted versus pressure‐limited ventilation in neonates 2017 · Cochrane Headline outcomes onlyno estimate extracted7 studies · 324 participantsModerate
Volume‐targeted showed no clear difference in any pH < 7.25 compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted probably leads to lower hypocarbia pCO2 < 35 mmHg/4.7 kPa compared with pressure‐limited ventilation: additional findings (moderate certainty).
Volume‐targeted showed no clear difference in respiratory acidosis pH < 7.25 and pCO2 > 60 mmHg/8 kPa compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted showed no clear difference in either hypocarbia or respiratory acidosis compared with pressure‐limited ventilation: additional findings; GRADE not reported.
Volume‐targeted showed no clear difference in patent ductus arteriosus compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted showed no clear difference in air leak (any) compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted showed no clear difference in pulmonary interstitial emphysema compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted probably leads to lower death or BPD (36 weeks) compared with pressure‐limited ventilation: main findings (moderate certainty).
Volume‐targeted showed no clear difference in any IVH compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted probably leads to lower PVL compared with pressure‐limited ventilation: additional findings (moderate certainty).
Volume‐targeted showed no clear difference in any IVH or PVL compared with pressure‐limited ventilation: additional findings (moderate certainty).
Volume‐targeted showed no clear difference in BPD (supplemental oxygen at 28 days) compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted probably leads to lower pneumothorax compared with pressure‐limited ventilation: main findings (moderate certainty).
Volume‐targeted probably leads to lower IVH grade 3‐4 compared with pressure‐limited ventilation: main findings (moderate certainty).
Volume‐targeted probably leads to lower IVH grade 3‐4 or PVL compared with pressure‐limited ventilation: main findings (moderate certainty).
Volume‐targeted may leads to lower BPD (supplemental oxygen at 36 weeks) compared with pressure‐limited ventilation: main findings (low certainty).
Volume‐targeted showed no clear difference in death or BPD (28 days) compared with pressure‐limited ventilation: additional findings (low certainty).
Volume‐targeted showed no clear difference in failure of mode of ventilation compared with pressure‐limited ventilation: additional findings (moderate certainty).
Arginine probably leads to lower NEC any stage Bell's criteria compared with placebo (moderate certainty).