What do systematic reviews say?

Intervention not reported

It is very uncertain whether the intervention changes minimally invasive step‐up approach: video‐assisted vs. endoscopic (very low certainty).

• Interventions for necrotising pancreatitis 2016 · Cochrane Headline outcomes only
  OR 4.5 [0.41, 49.08]
  1 study · 22 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes minimally invasive step‐up approach: planned surgery vs. continued… (very low certainty).

• Interventions for necrotising pancreatitis 2016 · Cochrane Headline outcomes only
  OR 21 [0.64, 689.99]
  1 study · 8 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes minimally invasive step‐up approach vs. open necrosectomy (very low certainty).

• Interventions for necrotising pancreatitis 2016 · Cochrane Headline outcomes only
  OR 0.38 [0.14, 1.01]
  1 study · 72 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes peritoneal lavage vs. open necrosectomy (very low certainty).

• Interventions for necrotising pancreatitis 2016 · Cochrane Headline outcomes only
  Rate ratio 1.28 [0.92, 1.78]
  2 studies · 56 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes minimally invasive step‐up approach: video‐assisted vs. endoscopic (very low certainty).

• Interventions for necrotising pancreatitis 2016 · Cochrane Headline outcomes only
  Rate ratio 12.55 [0.72, 219.54]
  1 study · 22 participants
  Very low

Laparoscopic gastrectomy vs open gastrectomy

Laparoscopic gastrectomy showed no clear difference in short‐term mortality compared with open gastrectomy (low certainty).

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  RR 1.6 [0.5, 5.1]
  11 studies · 2335 participants
  Low

Laparoscopic gastrectomy vs open gastrectomy

It is very uncertain whether laparoscopic gastrectomy changes long‐term mortality (maximal compared with open gastrectomy (very low certainty).

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  HR 0.94 [0.7, 1.25]
  3 studies · 195 participants
  Very low

Laparoscopic gastrectomy vs open gastrectomy

It is very uncertain whether laparoscopic gastrectomy changes proportion with a serious adverse event (< 3 months) compared with open gastrectomy (very low certainty).

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  RR 0.6 [0.27, 1.34]
  8 studies · 432 participants
  Very low

Laparoscopic gastrectomy vs open gastrectomy

It is very uncertain whether laparoscopic gastrectomy changes long‐term recurrence (maximal compared with open gastrectomy (very low certainty).

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  HR 0.95 [0.7, 1.3]
  4 studies · 162 participants
  Very low

Laparoscopic gastrectomy vs open gastrectomy

It is very uncertain whether laparoscopic gastrectomy changes proportion with an adverse event (< 3 months) compared with open gastrectomy (very low certainty).

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  RR 0.78 [0.6, 1.01]
  11 studies · 2490 participants
  Very low

Laparoscopic gastrectomy vs open gastrectomy

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 143 participants
  Very low

Laparoscopic gastrectomy vs open gastrectomy

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 319 participants
  Very low

Laparoscopic gastrectomy vs open gastrectomy

• Laparoscopic versus open gastrectomy for gastric cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 472 participants
  Very low

Laparoscopic vs open transhiatal oesophagectomy

It is very uncertain whether laparoscopic changes short‐term mortality (in hospital or within 3 months) compared with open transhiatal oesophagectomy (very low certainty).

• Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
  RR 0.44 [0.05, 4.09]
  5 studies · 326 participants
  Very low

Laparoscopic vs open transhiatal oesophagectomy

• Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 266 participants
  Very low

Laparoscopic vs open transhiatal oesophagectomy

It is very uncertain whether laparoscopic changes positive resection margins compared with open transhiatal oesophagectomy (very low certainty).

• Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
  RR 0.65 [0.37, 1.12]
  3 studies · 213 participants
  Very low

Laparoscopic vs open transhiatal oesophagectomy

• Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 326 participants
  Very low

Laparoscopic vs open transhiatal oesophagectomy

It is very uncertain whether laparoscopic changes long‐term mortality compared with open transhiatal oesophagectomy (very low certainty).

• Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
  HR 0.97 [0.81, 1.16]
  2 studies · 193 participants
  Very low

Laparoscopic vs open transhiatal oesophagectomy

It is very uncertain whether laparoscopic changes serious adverse events (proportion) compared with open transhiatal oesophagectomy (very low certainty).

• Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
  RR 0.49 [0.24, 0.99]
  3 studies · 213 participants
  Very low

Laparoscopic vs open transhiatal oesophagectomy

It is very uncertain whether laparoscopic changes anastomotic stenosis compared with open transhiatal oesophagectomy (very low certainty).

• Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
  RR 1.37 [0.33, 5.7]
  1 study · 73 participants
  Very low