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Evidence found and GRADE certainty

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

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No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Supervised exercise therapy following vascular intervention vs vascular intervention alone

All‐cause mortality · people with symptomatic peripheral arterial disease§

It is very uncertain whether supervised exercise therapy following vascular intervention changes mortality compared with vascular intervention alone (very low certainty).

1 finding from 1 review

Supervised exercise therapy following vascular intervention vs vascular intervention alone

Reintervention · people with symptomatic peripheral arterial disease§

It is very uncertain whether supervised exercise therapy following vascular intervention changes reintervention compared with vascular intervention alone (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Purse‐string skin closure vs linear skin closure

Surgical site infection · people undergoing stoma reversal

Summary of findings table ‐ Purse‐string skin closure probably leads to lower surgical site infection compared with linear skin closure (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Purse‐string skin closure vs linear skin closure

Participant satisfaction (very satisfied or satisfied) · people undergoing stoma reversal

Summary of findings table ‐ Purse‐string skin closure may leads to higher participant satisfaction (very satisfied or satisfied) compared with linear skin closure (low certainty).

1 finding from 1 review

Summary of findings table ‐ Purse‐string skin closure vs linear skin closure

Incisional hernia · people undergoing stoma reversal

It is very uncertain whether summary of findings table ‐ Purse‐string skin closure changes incisional hernia compared with linear skin closure (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics

Mortality before hospital discharge · adults (aged greater than 18 years) with acute heart failure

Summary of findings table ‐ Continuous infusion of intravenous loop… showed no clear difference in all‐cause mortality (from admission to discharge) compared with bolus injection of intravenous loop diuretics (low certainty).

1 finding from 1 review

Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics

Hospital readmission · adults (aged greater than 18 years) with acute heart failure

Summary of findings table ‐ Continuous infusion of intravenous loop… showed no clear difference in readmission to hospital following discharge compared with bolus injection of intravenous loop diuretics (low certainty).

1 finding from 1 review

Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics

Acute kidney injury · adults (aged greater than 18 years) with acute heart failure

Summary of findings table ‐ Continuous infusion of intravenous loop… showed no clear difference in acute kidney injury (adverse event) (from admission to discharge) compared with bolus injection of intravenous loop diuretics (low certainty).

1 finding from 1 review

Zinc vs placebo

Risk of adverse events, including those that may be due to zinc supplements Duration of · adults and children with colds and/or upper respiratory infections
1 finding from 1 review

Zinc vs placebo

Risk of serious adverse events, including those that may be complications of the common cold · adults and children with colds and/or upper respiratory infections

The review found no eligible studies for this question.

1 finding from 1 review