Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,923 questions · 1,956 findings · 143 reviews · Musculoskeletal

No studies found 555 · 28.4%GRADE not reported 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Intervention not reported

Pain reduction 10 cm VAS. Scale from: 0 to 10 cm (0 is no pain). · patients with acute gout
1 finding from 1 review

Intervention not reported

Number of participant withdrawals due to adverse events ‐ not measured · patients with acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Reduction of joint inflammation Tape measure ‐ joint circumference (cm) · patients with acute gout
1 finding from 1 review

Intervention not reported

Joint function ‐ not measured · patients with acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Health‐related quality of life ‐ not measured · patients with acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Patient global assessment ‐ not measured · patients with acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Serious adverse events ‐ not measured · patients with acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events Event episodes (n) reported · patients with osteoarthritis of the knee

The intervention probably leads to higher adverse events Event episodes (n) reported (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of Life · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain VAS 0‐100 (higher means worse) · patients with osteoarthritis of the knee
1 finding from 1 review

Intervention not reported

Function: change from baseline WOMAC VAS (Function; higher means worse) · patients with osteoarthritis of the knee
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported adverse events · patients with osteoarthritis of the knee

The intervention showed no clear difference in adverse events Participants (n) reported adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis of the knee

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life SF‐36 4 · patients with osteoarthritis of the knee
1 finding from 1 review