Findings

What do systematic reviews say?

2,079 questions · 2,112 findings · 171 reviews · Eyes and Vision

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No studies found 587 · 27.8%GRADE not reported 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

Summary of findings: autologous serum vs Normal saline

Adverse events · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: autologous serum vs artificial tears

Tear hyperosmolarity · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: autologous serum vs artificial tears

Fluorescein staining Range of scale: 0‐9, where a higher score is worse · people with dry eye

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Summary of findings: autologous serum vs artificial tears

Rose Bengal staining Range of scale: 0‐9, where a higher score is worse · people with dry eye

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Summary of findings: autologous serum vs artificial tears

Tear film stability · people with dry eye

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Summary of findings: autologous serum vs artificial tears

Schirmer’s test Score < 4 mm indicates severe dry eye · people with dry eye

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Summary of findings: autologous serum vs artificial tears

Adverse events · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: autologous serum vs Normal saline

Participant‐reported symptoms · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: autologous serum vs Normal saline

Tear hyperosmolarity · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Autologous serum eye drops for dry eye 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical NSAIDs vs control

Reduction in pain intensity · analgesia in traumatic corneal abrasions

The review found no eligible studies for this question.

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical NSAIDs vs control

Rescue analgesia · analgesia in traumatic corneal abrasions

Topical NSAIDs may leads to lower use of rescue oral analgesia at 24 hours compared with control (low certainty).

2 findings from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 0.46 [0.34, 0.61]
4 studies · 481 participants
Low
Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical NSAIDs vs control

Proportion of abrasions healed after 24 hours · analgesia in traumatic corneal abrasions

Topical NSAIDs showed no clear difference in proportion of abrasions healed after 24 hours compared with control (low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 1 [0.81, 1.23]
1 study · 28 participants
Low

Topical NSAIDs vs control

Proportion of abrasions healed after 48 hours · analgesia in traumatic corneal abrasions

Topical NSAIDs showed no clear difference in proportion of abrasions healed after 48 hours compared with control (low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 1 [0.88, 1.14]
1 study · 28 participants
Low

Topical NSAIDs vs control

Complications of corneal abrasion · analgesia in traumatic corneal abrasions

It is very uncertain whether topical NSAIDs changes complications of corneal abrasion compared with control (very low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 0.44 [0.07, 2.96]
6 studies · 609 participants
Very low

Topical NSAIDs vs control

Adverse drug events · analgesia in traumatic corneal abrasions

It is very uncertain whether topical NSAIDs changes drug‐related adverse events compared with control (very low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 2.95 [0.32, 27.6]
2 studies · 163 participants
Very low

Larger coaxial microincision cataract surgery (C‐MICS) vs standard phacoemulsification

Mean postoperative surgically induced astigmatism · people with age‐related cataract

1 finding from 1 review

Different‐sized incisions for phacoemulsification in age‐related cataract 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Smaller coaxial microincision cataract surgery (C‐MICS) vs standard phacoemulsification

Mean change of central corneal thickness · people with age‐related cataract

1 finding from 1 review

Different‐sized incisions for phacoemulsification in age‐related cataract 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Smaller coaxial microincision cataract surgery (C‐MICS) vs standard phacoemulsification

Adverse events · people with age‐related cataract

The review found no eligible studies for this question.

1 finding from 1 review

Different‐sized incisions for phacoemulsification in age‐related cataract 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Smaller coaxial microincision cataract surgery (C‐MICS) vs standard phacoemulsification

Quality of life · people with age‐related cataract

The review found no eligible studies for this question.

1 finding from 1 review

Different‐sized incisions for phacoemulsification in age‐related cataract 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Smaller coaxial microincision cataract surgery (C‐MICS) vs larger C‐MICS

Mean postoperative surgically induced astigmatism · people with age‐related cataract

1 finding from 1 review

Different‐sized incisions for phacoemulsification in age‐related cataract 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low