Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Continuous glucose monitoring system vs intermittent glucose monitoring

Perinatal mortality · women with pre‐existing diabetes

Continuous glucose monitoring showed no clear difference in perinatal mortality (stillbirth and neonatal mortality) compared with intermittent glucose monitoring (low certainty).

1 finding from 1 review

Self‐monitoring vs a different type of self‐monitoring

Perinatal mortality · women with pre‐existing diabetes

It is very uncertain whether self‐monitoring changes perinatal mortality (stillbirth and neonatal mortality) compared with a different type of self‐monitoring (very low certainty).

1 finding from 1 review

Self‐monitoring at home vs hospitalisation

Hypertensive disorders of pregnancy · women with pre‐existing diabetes

It is very uncertain whether self‐monitoring at home changes hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with hospitalisation (very low certainty).

1 finding from 1 review

Calcium supplementation/fortification vs placebo (outcomes

Pre‐eclampsia · women who are not yet pregnant and women in the early stages of pregnancy

Calcium supplementation showed no clear difference in pre‐eclampsia compared with placebo (maternal outcomes) commencing before or early (low certainty).

1 finding from 1 review

Calcium supplementation/fortification vs placebo (outcomes

Pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at any gestational age · women who are not yet pregnant and women in the early stages of pregnancy

Calcium supplementation showed no clear difference in pre‐eclampsia, or pregnancy loss, or stillbirth (or combination) at… compared with placebo (maternal outcomes) commencing before or early (low certainty).

1 finding from 1 review

Calcium supplementation/fortification vs placebo (outcomes

Severe maternal morbidity and mortality index · women who are not yet pregnant and women in the early stages of pregnancy

Calcium supplementation showed no clear difference in severe maternal morbidity and mortality index compared with placebo (maternal outcomes) commencing before or early (low certainty).

1 finding from 1 review

Calcium supplementation/fortification vs placebo (outcomes

Pregnancy loss or stillbirth at any gestational age · women who are not yet pregnant and women in the early stages of pregnancy

Calcium supplementation showed no clear difference in pregnancy loss or stillbirth at any gestational age compared with placebo (maternal outcomes) commencing before or early (low certainty).

1 finding from 1 review