Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

161 questions · 165 findings · 15 reviews · Childhood Cancer

No studies found 50 · 30.3%GRADE not reported 12 · 7.3%Very low 13 · 7.9%Low 69 · 41.8%Moderate 21 · 12.7%High 0 · 0%

Very early discharge vs early discharge

Treatment failure; rehospitalization or adjustment of antimicrobial treatment (or both) in number of episodes · children with cancer

Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).

1 finding from 1 review

Very early discharge vs early discharge

Treatment failure; rehospitalization or adjustment of antimicrobial treatment (or both), only first episode in number of participants · children with cancer

Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).

1 finding from 1 review

Physical exercise training vs usual care

Fatigue · children and young adults during and after treatment for childhood cancer
2 findings from 1 review

Intracystic bleomycin vs other types of intracystic treatment

Total number of adverse effects · cystic craniopharyngiomas in children from birth to 18 years old

It is very uncertain whether intracystic bleomycin changes total number of adverse effects compared with other types of intracystic treatment (very low certainty).

1 finding from 1 review