Cochrane · systematic review · CD008890
Intracystic bleomycin for cystic craniopharyngiomas in children
Zhang, S, Fang, Y, Cai, BW, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Childhood CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Intracystic bleomycin compared to other types of intracystic treatment for cystic craniopharyngiomas in children
Population: cystic craniopharyngiomas in children from birth to 18 years old
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Survival Intracystic bleomycin vs other types of intracystic treatment | no estimate extracted | NR | No studies |
Change in cyst size Intracystic bleomycin vs other types of intracystic treatment | no estimate extracted | 1 study · 7 participants | Very low Downgraded: risk of bias, imprecision |
Neurological status Intracystic bleomycin vs other types of intracystic treatment | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Total number of adverse effects Intracystic bleomycin vs other types of intracystic treatment | RR 1.75 [0.68, 4.53] | 1 study · 7 participants | Very low Downgraded: risk of bias, imprecision |
Fever Intracystic bleomycin vs other types of intracystic treatment | RR 2.92 [0.73, 11.7] | 1 study · 7 participants | Very low Downgraded: risk of bias, imprecision |
3rd nerve paralysis Intracystic bleomycin vs other types of intracystic treatment | no estimate extracted | 1 study · 7 participants | Very low Downgraded: risk of bias, imprecision |
Headache and vomiting Intracystic bleomycin vs other types of intracystic treatment | no estimate extracted | 1 study · 7 participants | Very low Downgraded: risk of bias, imprecision |