NEC ≥ stage II · preterm infants
Early treatment showed no clear difference in necrotizing enterocolitis (NEC; stage 2 or greater) compared with expectant management (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm infants
Very early treatment showed no clear difference in all‐cause mortality during hospital stay compared with expectant management (moderate certainty).
1 finding from 1 review
Proportion of infants requiring surgical PDA ligation or transcatheter occlusion · preterm infants
Very early treatment showed no clear difference in proportion of infants requiring surgical PDA ligation or… compared with expectant management (moderate certainty).
1 finding from 1 review
Proportion of infants receiving any pharmacotherapy for a hemodynamically significant PDA · preterm infants
It is very uncertain whether very early treatment changes proportion of infants receiving any pharmacotherapy for a… compared with expectant management (very low certainty).
1 finding from 1 review
Days to regain birth weight · preterm infants
1 finding from 1 review
Linear growth (cm/week) · preterm infants
1 finding from 1 review
Growth: head circumference (cm/week) · preterm infants
1 finding from 1 review
Risk of necrotising enterocolitis stage ≥ 2 · preterm infants
Early showed no clear difference in necrotising enterocolitis stage 2 or 3 compared with late fortification of human milk (low certainty).
1 finding from 1 review
Time to achieve full enteral feeding (days) · preterm infants
1 finding from 1 review
Extrauterine growth restriction at discharge · preterm infants
Early showed no clear difference in extrauterine growth restriction at discharge compared with late fortification of human milk (low certainty).
1 finding from 1 review
Proportion of infants with feed interruption episodes · preterm infants
Early showed no clear difference in proportion of infants with feed interruption episodes compared with late fortification of human milk (low certainty).
1 finding from 1 review
Rate of weight gain (g/kg/day) · promoting growth and development in very low birth weight infants receiving human milk
1 finding from 1 review
Rate of weight gain (g/kg/day) · promoting growth and development in very low birth weight infants receiving human milk
1 finding from 1 review
Linear growth (cm/week) · promoting growth and development in very low birth weight infants receiving human milk
1 finding from 1 review
Growth velocity, head circumference, mm/d, end of intervention · promoting growth and development in very low birth weight infants receiving human milk
1 finding from 1 review
Length of hospital stay · promoting growth and development in very low birth weight infants receiving human milk
1 finding from 1 review
Retinopathy of prematurity · promoting growth and development in very low birth weight infants receiving human milk
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Bronchopulmonary dysplasia · promoting growth and development in very low birth weight infants receiving human milk
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · promoting growth and development in very low birth weight infants receiving human milk
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
In‐hospital mortality · promoting growth and development in very low birth weight infants receiving human milk
It is very uncertain whether targeted individualized changes in‐hospital mortality compared with standard non‐individualized fortification (very low certainty).
1 finding from 1 review