Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,281 questions · 1,361 findings · 120 reviews · Developmental, Psychosocial and Learning Problems

No studies found 286 · 21%GRADE not reported 61 · 4.5%Very low 381 · 28%Low 381 · 28%Moderate 228 · 16.8%High 24 · 1.8%

Intermittent use of iron supplements vs placebo or no intervention

Anaemia · children under 12 years of age

Intermittent use of iron supplements probably leads to lower anaemia (haemoglobin below a cut‐off defined by trialists, taking… compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Iron deficiency (using ferritin concentrations) · children under 12 years of age

It is very uncertain whether intermittent use of iron supplements changes iron deficiency (using ferritin concentrations) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Iron status (ferritin concentrations in ng/mL) · children under 12 years of age

Intermittent use of iron supplements may leads to higher iron status (ferritin (μg/L) compared with placebo or no intervention (low certainty).

1 finding from 1 review

Intermittent vs any daily iron supplementation

Iron deficiency (using ferritin concentrations) · children under 12 years of age

It is very uncertain whether intermittent changes iron deficiency (using ferritin concentrations) compared with daily use of iron supplements (very low certainty).

1 finding from 1 review

Intervention not reported

Aggression OAS, OAS‐M, MOAS, self‐reported incidents, CPRS subscale (endpoints fall between 2 weeks and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
1 finding from 1 review

Intervention not reported

Impulsivity Q‐sort, Porteus Maze Test (endpoints fall between 2 weeks and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
1 finding from 1 review

Intervention not reported

Hostility BPRS hostility sub scale, CPRS hostility subscale, Q‐sort, speech content analysis (endpoints fall between 1 and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
1 finding from 1 review

Intervention not reported

Anger Self‐reported outbursts, Rosenweig Picture Frustration Test (endpoints fall between 2 weeks and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
1 finding from 1 review

Intervention not reported

Anger‐Hostility POMS anger‐hostility subscale (endpoints fall between 1 and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
1 finding from 1 review

Intervention not reported

Non‐compliance leaving the study early (endpoints fall between 1 and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
1 finding from 1 review

Intervention not reported

Adverse events, any (endpoints fall between 1 6 six months) · Any individual experiencing recurrent aggressive outbursts or episodes
1 finding from 1 review